Exosomes play essential roles in intercellular communications. The exosome was
discovered in 1983, when it was found that reticulocytes release 50-nm small vesicles …

Tumors are not isolated entities, but complex systemic networks involving cell-cell
communication between transformed and non-transformed cells. The milieu created by …

Humans circulate quadrillions of exosomes at all times. Exosomes are a class of
extracellular vesicles released by all cells, with a size range of 40–150 nm and a lipid …

Abstract Development of functional nanomaterials is of great importance and significance for
advanced drug delivery and therapy. Nevertheless, exogenous nanomaterials have a great …

Extracellular vesicles (EVs) represent a novel mechanism of intercellular communication as
vehicles for intercellular transfer of functional membrane and cytosolic proteins, lipids, and …

Exosomes are nanosized extracellular vesicles of endosomal origin that enclose a multitude
of functional biomolecules. Exosomes have emerged as key players of intercellular …

Exosomes, a subset of extracellular vesicles (EVs), function as a mode of intercellular
communication and molecular transfer. Exosomes facilitate the direct extracellular transfer of …

Sepsis is an infection-induced severe inflammatory disorder that leads to multiple organ
failure. Amongst organs affected, myocardial depression is believed to be a major …

The genetic modification of T cells has advanced cellular immunotherapies, yet the delivery
of biologics specifically to T cells remains challenging. Here we report a suite of methods for …

Reactive oxygen species (ROS) play a key signal transduction role in cells. They are
involved in the regulation of growth, development, responses to environmental stimuli and …