Eosinophilic airway inflammation: role in asthma and chronic obstructive pulmonary disease

L George, CE Brightling - Therapeutic advances in chronic …, 2016 - journals.sagepub.com
The chronic lung diseases, asthma and chronic obstructive pulmonary disease (COPD), are
common affecting over 500 million people worldwide and causing substantial morbidity and …

The paradoxes of asthma management: time for a new approach?

PM O'Byrne, C Jenkins… - European Respiratory …, 2017 - Eur Respiratory Soc
Poor adherence to maintenance pharmacotherapy is a reality in asthma. Studies confirm
that when symptoms worsen, most patients increase short-acting β2-agonist (SABA) use …

Canadian Thoracic Society 2012 guideline update: diagnosis and management of asthma in preschoolers, children and adults

MD Lougheed, C Lemiere… - Canadian respiratory …, 2012 - Wiley Online Library
BACKGROUND: In 2010, the Canadian Thoracic Society (CTS) published a Consensus
Summary for the diagnosis and management of asthma in children six years of age and …

Efficacy and safety of maintenance and reliever combination budesonide–formoterol inhaler in patients with asthma at risk of severe exacerbations: a randomised …

M Patel, J Pilcher, A Pritchard, K Perrin… - The Lancet …, 2013 - thelancet.com
Summary Background The Single combination budesonide–formoterol inhaler Maintenance
And Reliever Therapy (SMART) regimen reduces severe asthma exacerbations in patients …

Combination formoterol and budesonide as maintenance and reliever therapy versus combination inhaler maintenance for chronic asthma in adults and children

KM Kew, C Karner, SM Mindus… - Cochrane Database of …, 2013 - cochranelibrary.com
Background Asthma is characterised by chronic inflammation of the airways and recurrent
exacerbations with wheezing, chest tightness and cough. Treatment with inhaled steroids …

[HTML][HTML] New versus old: the impact of changing patterns of inhaled corticosteroid prescribing and dosing regimens in asthma management

D Singh, G Garcia, K Maneechotesuwan… - Advances in …, 2022 - Springer
Inhaled corticosteroid (ICS)-containing therapies are the mainstay of pharmacological
management of asthma. They can be administered alone or in combination with a long …

Combination of budesonide/formoterol on demand improves asthma control by reducing exercise-induced bronchoconstriction

N Lazarinis, L Jørgensen, T Ekström, L Bjermer… - Thorax, 2014 - thorax.bmj.com
Background In mild asthma exercise-induced bronchoconstriction (EIB) is usually treated
with inhaled short-acting β2 agonists (SABAs) on demand. Objective The hypothesis was …

Comparative effectiveness of long term drug treatment strategies to prevent asthma exacerbations: network meta-analysis

RJB Loymans, A Gemperli, J Cohen, SM Rubinstein… - Bmj, 2014 - bmj.com
Objective To determine the comparative effectiveness and safety of current maintenance
strategies in preventing exacerbations of asthma. Design Systematic review and network …

Lipid metabolism in asthma: immune regulation and potential therapeutic target

WJ Li, Y Zhao, Y Gao, LL Dong, YF Wu, ZH Chen… - Cellular …, 2021 - Elsevier
Asthma is a chronic inflammatory disease of the lungs that poses a considerable health and
socioeconomic burden. Several risk factors work synergistically to affect the progression of …

The lag-time approach improved drug–outcome association estimates in presence of protopathic bias

A Arfè, G Corrao - Journal of clinical epidemiology, 2016 - Elsevier
Objectives Protopathic bias is a systematic error which occurs when measured exposure
status may be affected by the latent onset of the target outcome. In this article, we aimed to …