C-reactive protein (CRP) is an acute inflammatory protein that increases up to 1,000-fold at
sites of infection or inflammation. CRP is produced as a homopentameric protein, termed …

Arterial stiffness results from a degenerative process affecting mainly the extracellular matrix
of elastic arteries under the effect of aging and risk factors. Changes in extracellular matrix …

Peripheral arterial disease (PAD) increases the risk of lower extremity amputation. It is also
an independent predictor of cardiovascular and cerebrovascular ischemic events, affecting …

Endothelial nitric oxide synthase (eNOS) plays a critical role in regulating and maintaining a
healthy cardiovascular system. The importance of eNOS can be emphasized from the …

Purpose—The aim of this statement is to summarize data on stroke risk factors that are
unique to and more common in women than men and to expand on the data provided in …

The endothelium is considered to be the gatekeeper of the vessel wall, maintaining and
regulating vascular integrity. In patients with chronic kidney disease, protective endothelial …

Chronic inflammatory state in obesity causes dysregulation of the endocrine and paracrine
actions of adipocyte-derived factors, which disrupt vascular homeostasis and contribute to …

The prototypic acute-phase reactant C-reactive protein (CRP) has long been recognized as
a useful marker and gauge of inflammation. CRP also plays an important role in host …

C-reactive protein (CRP) is a phylogenetically highly conserved plasma protein, with
homologs in vertebrates and many invertebrates, that participates in the systemic response …

Endothelial dysfunction is characterized by a shift of the actions of the endothelium toward
reduced vasodilation, a proinflammatory state, and prothrombic properties. It is associated …