Construction of homo and heteronuclear Ru (II), Ir (III) and Re (I) complexes for target specific cancer therapy

S Pete, N Roy, B Kar, P Paira - Coordination Chemistry Reviews, 2022 - Elsevier
More than 10 million death tolls in 2020 were reported as a result of heinous impact of
cancer, making it second most prime cause of death after cardiovascular diseases. In …

Target-specific mononuclear and binuclear rhenium (i) tricarbonyl complexes as upcoming anticancer drugs

A Sharma, N Vaibhavi, B Kar, U Das, P Paira - RSC advances, 2022 - pubs.rsc.org
Metal complexes have gradually been attracting interest from researchers worldwide as
potential cancer therapeutics. Driven by the many side effects of the popular platinum-based …

Recent developments in the nanostructured materials functionalized with ruthenium complexes for targeted drug delivery to tumors

P Thangavel, B Viswanath, S Kim - International journal of …, 2017 - Taylor & Francis
In recent years, the field of metal-based drugs has been dominated by other existing
precious metal drugs, and many researchers have focused their attention on the synthesis of …

CuAAC “Click”-Derived Luminescent 2-(2-(4-(4-(Pyridin-2-yl)-1H-1,2,3-triazol-1-yl)butoxy)phenyl)benzo[d]thiazole-Based Ru(II)/Ir(III)/Re(I) Complexes as Anticancer …

L Thilak Babu, P Paira - ACS omega, 2023 - ACS Publications
To enhance the cytoselective behavior of the complexes, we intended to develop a CuAAC
“click”-derived synthetic protocol for the preparation of 2-(2-(4-(4-(pyridin-2-yl)-1 H-1, 2, 3 …

G2/M-Phase-Inhibitory Mitochondrial-Depolarizing Re (I)/Ru (II)/Ir (III)-2, 2′-Bipyrimidine-Based Heterobimetallic Luminescent Complexes: An Assessment of In Vitro …

N Roy, S Shanavas, B Kar, L Thilak Babu, U Das… - ACS …, 2023 - ACS Publications
Triple-negative breast cancer (TNBC) is an extremely vicious subtype of human breast
cancer having the worst prognosis along with strong invasive and metastatic competency …

Biological evaluation of platinum (II) sulfonamido complexes: synthesis, characterization, cytotoxicity, and biological imaging

C Maladeniya, T Darshani… - Bioinorganic …, 2022 - Wiley Online Library
Platinum‐based compounds are actively used in clinical trials as anticancer agents. In this
study, two novel platinum complexes,(C1=[PtCl2 (N (SO2quin) dpa)], C2=[PtCl2 (N …

Synthesis of novel coumarin nucleus-based DPA drug-like molecular entity: In vitro DNA/Cu(II) binding, DNA cleavage and pro-oxidant mechanism for anticancer …

S Khan, AM Malla, A Zafar, I Naseem - PloS one, 2017 - journals.plos.org
Despite substantial research on cancer therapeutics, systemic toxicity and drug-resistance
limits the clinical application of many drugs like cisplatin. Therefore, new chemotherapeutic …

Fluorescent di-(2-picolyl) amine based drug-like ligands and their Re (CO) 3 complexes towards biological applications

T Darshani, N Thushara, P Weerasuriya, FR Fronczek… - Polyhedron, 2020 - Elsevier
Herein we report two new fac-Re (I) tricarbonyl complexes, fac-[Re (CO) 3 (N (SO 2)(1-nap)
dpa)] PF 6 (C1) and fac-[Re (CO) 3 (N (SO 2)(2-nap) dpa)] PF 6 (C2), of two naphthalene …

Substituted bidentate and ancillary ligands modulate the bioimaging properties of the classical Re (i) tricarbonyl core with yeasts and bacteria

A Carreño, AE Aros, C Otero, R Polanco… - New Journal of …, 2017 - pubs.rsc.org
Rhenium (I) tricarbonyl complexes with heteroaromatic ligands have been intensely
investigated with respect to their properties as imaging probes, although they have only …

Phosphate and polyphosphate anion recognition by a dinuclear copper (ii) complex of an unsymmetrical squaramide

CV Esteves, J Costa, D Esteban-Gómez… - Dalton …, 2019 - pubs.rsc.org
In the search for receptors suitable for the recognition of phosphate or polyphosphate
anions, a new unsymmetrical squaramide-based ligand bearing dipicolylamine (dpa) and …