Plasticity of microglia

M Augusto‐Oliveira, GP Arrifano, CI Delage… - Biological …, 2022 - Wiley Online Library
Microglial cells are the scions of foetal macrophages which invade the neural tube early
during embryogenesis. The nervous tissue environment instigates the phenotypic …

The influence of maternal care on stress-related behaviors in domestic dogs: What can we learn from the rodent literature?

VH Czerwinski, BP Smith, PI Hynd, SJ Hazel - Journal of Veterinary …, 2016 - Elsevier
An estimated 40% of dogs living as companion dogs are believed to exhibit some form of
anxiety or stress-related behavior. Although this represents a significant welfare issue, our …

Stereological analysis of microglia in aged male and female fischer 344 rats in socially relevant brain regions

AE Perkins, MK Piazza, T Deak - Neuroscience, 2018 - Elsevier
Aging is associated with a substantial decline in the expression of social behavior as well as
increased neuroinflammation. Since immune activation and subsequent increased …

Diffuse traumatic axonal injury in the optic nerve does not elicit retinal ganglion cell loss

J Wang, MA Fox, JT Povlishock - Journal of Neuropathology & …, 2013 - academic.oup.com
Much of the morbidity after traumatic brain injury (TBI) is associated with traumatic axonal
injury (TAI). Although most TAI studies focus on corpus callosum white matter, the visual …

[11C]PBR28 PET Imaging is Sensitive to Neuroinflammation in the Aged Rat

MD Walker, K Dinelle, R Kornelsen… - Journal of Cerebral …, 2015 - journals.sagepub.com
Neuroinflammation in the aging rat brain was investigated using [11C] PBR28 microPET
(positron emission tomography) imaging. Normal rats were studied alongside LRRK2 p …

Brain aging and electrophysiological signaling: revisiting the spreading depression model

RCA Guedes, R Abadie-Guedes - Frontiers in Aging Neuroscience, 2019 - frontiersin.org
As a consequence of worldwide improvement in health care, the aging portion of the human
population has increased, now representing a higher proportion of the total population. This …

Neonatal l-glutamine modulates anxiety-like behavior, cortical spreading depression, and microglial immunoreactivity: analysis in developing rats suckled on normal …

DSC de Lima, ES Francisco, CB Lima, RCA Guedes - Amino Acids, 2017 - Springer
In mammals, l-glutamine (Gln) can alter the glutamate-Gln cycle and consequently brain
excitability. Here, we investigated in developing rats the effect of treatment with different …

Microglia and neurons in the hippocampus of migratory sandpipers

CG Diniz, NGM Magalhães, AA Sousa… - Brazilian Journal of …, 2015 - SciELO Brasil
The semipalmated sandpiper Calidris pusilla and the spotted sandpiper Actitis macularia
are long-and short-distance migrants, respectively. C. pusilla breeds in the sub-arctic and …

[HTML][HTML] Neonatal treatment with monosodium glutamate lastingly facilitates spreading depression in the rat cortex

CB Lima, GSF Soares, SM Vitor, B Castellano… - Life sciences, 2013 - Elsevier
Aims Monosodium glutamate (MSG) is a neuroexcitatory amino acid used in human food to
enhance flavor. MSG can affect the morphological and electrophysiological organization of …

[HTML][HTML] The Hidden Dangers of Sedentary Living: Insights into Molecular, Cellular, and Systemic Mechanisms

DG Diniz, J Bento-Torres, VO da Costa… - International Journal of …, 2024 - mdpi.com
With the aging of the global population, neurodegenerative diseases are emerging as a
major public health issue. The adoption of a less sedentary lifestyle has been shown to have …