Plasticity of microglia
Microglial cells are the scions of foetal macrophages which invade the neural tube early
during embryogenesis. The nervous tissue environment instigates the phenotypic …
during embryogenesis. The nervous tissue environment instigates the phenotypic …
The influence of maternal care on stress-related behaviors in domestic dogs: What can we learn from the rodent literature?
An estimated 40% of dogs living as companion dogs are believed to exhibit some form of
anxiety or stress-related behavior. Although this represents a significant welfare issue, our …
anxiety or stress-related behavior. Although this represents a significant welfare issue, our …
Stereological analysis of microglia in aged male and female fischer 344 rats in socially relevant brain regions
AE Perkins, MK Piazza, T Deak - Neuroscience, 2018 - Elsevier
Aging is associated with a substantial decline in the expression of social behavior as well as
increased neuroinflammation. Since immune activation and subsequent increased …
increased neuroinflammation. Since immune activation and subsequent increased …
Diffuse traumatic axonal injury in the optic nerve does not elicit retinal ganglion cell loss
Much of the morbidity after traumatic brain injury (TBI) is associated with traumatic axonal
injury (TAI). Although most TAI studies focus on corpus callosum white matter, the visual …
injury (TAI). Although most TAI studies focus on corpus callosum white matter, the visual …
[11C]PBR28 PET Imaging is Sensitive to Neuroinflammation in the Aged Rat
MD Walker, K Dinelle, R Kornelsen… - Journal of Cerebral …, 2015 - journals.sagepub.com
Neuroinflammation in the aging rat brain was investigated using [11C] PBR28 microPET
(positron emission tomography) imaging. Normal rats were studied alongside LRRK2 p …
(positron emission tomography) imaging. Normal rats were studied alongside LRRK2 p …
Brain aging and electrophysiological signaling: revisiting the spreading depression model
RCA Guedes, R Abadie-Guedes - Frontiers in Aging Neuroscience, 2019 - frontiersin.org
As a consequence of worldwide improvement in health care, the aging portion of the human
population has increased, now representing a higher proportion of the total population. This …
population has increased, now representing a higher proportion of the total population. This …
Neonatal l-glutamine modulates anxiety-like behavior, cortical spreading depression, and microglial immunoreactivity: analysis in developing rats suckled on normal …
DSC de Lima, ES Francisco, CB Lima, RCA Guedes - Amino Acids, 2017 - Springer
In mammals, l-glutamine (Gln) can alter the glutamate-Gln cycle and consequently brain
excitability. Here, we investigated in developing rats the effect of treatment with different …
excitability. Here, we investigated in developing rats the effect of treatment with different …
Microglia and neurons in the hippocampus of migratory sandpipers
CG Diniz, NGM Magalhães, AA Sousa… - Brazilian Journal of …, 2015 - SciELO Brasil
The semipalmated sandpiper Calidris pusilla and the spotted sandpiper Actitis macularia
are long-and short-distance migrants, respectively. C. pusilla breeds in the sub-arctic and …
are long-and short-distance migrants, respectively. C. pusilla breeds in the sub-arctic and …
[HTML][HTML] Neonatal treatment with monosodium glutamate lastingly facilitates spreading depression in the rat cortex
CB Lima, GSF Soares, SM Vitor, B Castellano… - Life sciences, 2013 - Elsevier
Aims Monosodium glutamate (MSG) is a neuroexcitatory amino acid used in human food to
enhance flavor. MSG can affect the morphological and electrophysiological organization of …
enhance flavor. MSG can affect the morphological and electrophysiological organization of …
[HTML][HTML] The Hidden Dangers of Sedentary Living: Insights into Molecular, Cellular, and Systemic Mechanisms
DG Diniz, J Bento-Torres, VO da Costa… - International Journal of …, 2024 - mdpi.com
With the aging of the global population, neurodegenerative diseases are emerging as a
major public health issue. The adoption of a less sedentary lifestyle has been shown to have …
major public health issue. The adoption of a less sedentary lifestyle has been shown to have …