Engineering microbial pathways for production of bio-based chemicals from lignocellulosic sugars: current status and perspectives

JM Francois, C Alkim, N Morin - Biotechnology for biofuels, 2020 - Springer
Lignocellulose is the most abundant biomass on earth with an annual production of about
2× 10 11 tons. It is an inedible renewable carbonaceous resource that is very rich in pentose …

Regulation Systems of Bacteria such as Escherichia coli in Response to Nutrient Limitation and Environmental Stresses

K Shimizu - Metabolites, 2013 - mdpi.com
An overview was made to understand the regulation system of a bacterial cell such as
Escherichia coli in response to nutrient limitation such as carbon, nitrogen, phosphate …

Ampicillin-controlled glucose metabolism manipulates the transition from tolerance to resistance in bacteria

M Jiang, Y Su, J Ye, H Li, S Kuang, J Wu, S Li… - Science …, 2023 - science.org
The mechanism (s) of how bacteria acquire tolerance and then resistance to antibiotics
remains poorly understood. Here, we show that glucose abundance decreases …

Proteome reallocation in Escherichia coli with increasing specific growth rate

K Peebo, K Valgepea, A Maser, R Nahku… - Molecular …, 2015 - pubs.rsc.org
Cells usually respond to changing growth conditions with a change in the specific growth
rate (μ) and adjustment of their proteome to adapt and maintain metabolic efficiency …

Current knowledge of the Escherichia coli phosphoenolpyruvate–carbohydrate phosphotransferase system: peculiarities of regulation and impact on growth and …

A Escalante, A Salinas Cervantes, G Gosset… - Applied microbiology …, 2012 - Springer
In Escherichia coli, the phosphoenolpyruvate–carbohydrate phosphotransferase system
(PTS) is responsible for the transport and phosphorylation of sugars, such as glucose. PTS …

Metabolic Regulation of a Bacterial Cell System with Emphasis on Escherichia coli Metabolism

K Shimizu - International Scholarly Research Notices, 2013 - Wiley Online Library
It is quite important to understand the overall metabolic regulation mechanism of bacterial
cells such as Escherichia coli from both science (such as biochemistry) and engineering …

Simultaneous fermentation of biomass-derived sugars to ethanol by a co-culture of an engineered Escherichia coli and Saccharomyces cerevisiae

L Wang, SW York, LO Ingram, KT Shanmugam - Bioresource Technology, 2019 - Elsevier
Microorganisms ferment xylose at high rate only when glucose concentration in the medium
falls below a critical level. Since the specific productivity of product is highest during …

Persister cells resuscitate using membrane sensors that activate chemotaxis, lower cAMP levels, and revive ribosomes

R Yamasaki, S Song, MJ Benedik, TK Wood - Iscience, 2020 - cell.com
Persistence, the stress-tolerant state, is arguably the most vital phenotype since nearly all
cells experience nutrient stress, which causes a sub-population to become dormant …

Simultaneous utilization of glucose and xylose via novel mechanisms in engineered Escherichia coli

SM Kim, BY Choi, YS Ryu, SH Jung, JM Park… - Metabolic …, 2015 - Elsevier
After glucose, xylose is the most abundant sugar in lignocellulosic carbon sources.
However, wild-type Escherichia coli is unable to simultaneously utilize both sugars due to …

Engineering an in vivo EP-bifido pathway in Escherichia coli for high-yield acetyl-CoA generation with low CO2 emission

Q Wang, J Xu, Z Sun, Y Luan, Y Li, J Wang, Q Liang… - Metabolic …, 2019 - Elsevier
The low carbon yield from native metabolic machinery produces unfavorable process
economics during the biological conversion of substrates to desirable bioproducts. To obtain …