Significance: Oxygen is indispensable for aerobic life, but its utilization exposes cells and
tissues to oxidative stress; thus, tight regulation of cellular, tissue, and systemic oxygen …

This review presents information that is useful to athletes, coaches and exercise scientists in
the adoption of exercise protocols, prescription of training regimens and creation of research …

It has been hypothesized that one reason for decreased ̇ VO _ 2\max in hypoxia could be
the lower maximal exercise intensity achieved in incremental, time or distance trial tests. We …

The capacity to extract oxygen from the environment and transport it to respiring tissues in
support of metabolic demand reportedly has implications for species' thermal tolerance …

Humans elicit a robust series of physiological responses to maintain adequate oxygen
delivery during hypoxia, including a transient reduction in hemoglobin-oxygen (Hb-O2) …

Sildenafil causes pulmonary vasodilation, thus potentially reducing impairments of hypoxia-
induced pulmonary hypertension on exercise performance at altitude. The purpose of this …

This report aims to summarise the scientific knowledge around hydration, nutrition, and
metabolism at high altitudes and to transfer it into the practical context of extreme altitude …

The mechanical power for cycling (P c) at constant ground speed (s), in the absence of wind
on smooth hard terrain is the sum of the power dissipated against rolling resistance, gravity …

Abstract Amann, Markus, and Bengt Kayser. Nervous system function during exercise in
hypoxia. High Alt. Med. Biol. 10: 149-164, 2009.—Aerobic exercise capacity decreases with …

It was the Summer Olympic Games 1968 held in Mexico City (2,300 m) that required
scientists and coaches to cope with the expected decline of performance in endurance …