Antibiotic resistance: turning evolutionary principles into clinical reality
Antibiotic resistance is one of the major challenges facing modern medicine worldwide. The
past few decades have witnessed rapid progress in our understanding of the multiple factors …
past few decades have witnessed rapid progress in our understanding of the multiple factors …
Roadmap to the bioanalytical testing of COVID-19: from sample collection to disease surveillance
The disease caused by SARS-CoV-2, coronavirus disease 2019 (COVID-19), has led to a
global pandemic with tremendous mortality, morbidity, and economic loss. The current lack …
global pandemic with tremendous mortality, morbidity, and economic loss. The current lack …
A novel “signal on-off-super on” sandwich-type aptamer sensor of CRISPR-Cas12a coupled voltage enrichment assay for VEGF detection
G Yuan, X Xia, J Zhang, J Huang, F Xie, X Li… - Biosensors and …, 2023 - Elsevier
Vascular endothelial growth factor (VEGF) plays an important role in atherosclerosis, and
the detection of VEGF is critical for the prevention, monitoring, and diagnosis of …
the detection of VEGF is critical for the prevention, monitoring, and diagnosis of …
Multivalent duplexed-aptamer networks regulated a CRISPR-Cas12a system for circulating tumor cell detection
Z Lv, Q Wang, M Yang - Analytical Chemistry, 2021 - ACS Publications
Although circulating tumor cells (CTCs) have great potential to act as the mini-invasive liquid
biopsy cancer biomarker, a rapid and sensitive CTC detection method remains lacking …
biopsy cancer biomarker, a rapid and sensitive CTC detection method remains lacking …
Highly sensitive and rapid detection of SARS‐CoV‐2 via a portable CRISPR‐Cas13a‐based lateral flow assay
H Liu, S Chang, S Chen, Y Du, H Wang… - Journal of Medical …, 2022 - Wiley Online Library
To rapidly identify individuals infected with severe acute respiratory syndrome coronavirus‐2
(SARS‐CoV‐2) and control the spread of coronavirus disease (COVID‐19), there is an …
(SARS‐CoV‐2) and control the spread of coronavirus disease (COVID‐19), there is an …
A rapid and high-throughput Helicobacter pylori RPA-CRISPR/Cas12a-based nucleic acid detection system
H Liu, J Wang, X Hu, X Tang, C Zhang - Clinica Chimica Acta, 2023 - Elsevier
Background Helicobacter pylori lives in the human stomach and causes gastric cancer and
other gastric diseases. The development of molecular technology has facilitated low-cost …
other gastric diseases. The development of molecular technology has facilitated low-cost …
CRISPR-cas technology: A key approach for SARS-CoV-2 detection
L Fang, L Yang, M Han, H Xu, W Ding… - … in bioengineering and …, 2023 - frontiersin.org
The CRISPR (Clustered Regularly Spaced Short Palindromic Repeats) system was first
discovered in prokaryotes as a unique immune mechanism to clear foreign nucleic acids. It …
discovered in prokaryotes as a unique immune mechanism to clear foreign nucleic acids. It …
Point-of-care testing for infectious diseases based on class 2 CRISPR/Cas technology
The early detection of infectious diseases and microorganisms is critical for effective disease
treatment, control, and prevention. Currently, nucleic acid testing and antigen–antibody …
treatment, control, and prevention. Currently, nucleic acid testing and antigen–antibody …
CRISPR/Cas9-based lateral flow and fluorescence diagnostics
MJ Osborn, A Bhardwaj, SP Bingea, F Knipping… - Bioengineering, 2021 - mdpi.com
Clustered regularly interspaced short palindromic repeat (CRISPR/Cas) proteins can be
designed to bind specified DNA and RNA sequences and hold great promise for the …
designed to bind specified DNA and RNA sequences and hold great promise for the …
Effective use of linear DNA in cell-free expression systems
MA McSweeney, MP Styczynski - Frontiers in Bioengineering and …, 2021 - frontiersin.org
Cell-free expression systems (CFEs) are cutting-edge research tools used in the
investigation of biological phenomena and the engineering of novel biotechnologies. While …
investigation of biological phenomena and the engineering of novel biotechnologies. While …