Labeling strategies of peptides with 18F for positron emission tomography

DE Olberg, OK Hjelstuen - Current topics in medicinal …, 2010 - ingentaconnect.com
A variety of peptides labeled with the positron emitting radionuclide fluorine-18 have shown
promise as tracers for use in positron emission tomography (PET) for the detection of …

Watching proteins in the wild: fluorescence methods to study protein dynamics in living cells

C Chamberlain, KM Hahn - Traffic, 2000 - Wiley Online Library
The advent of GFP imaging has led to a revolution in the study of live cell protein dynamics.
Ease of access to fluorescently tagged proteins has led to their widespread application and …

Convergent synthesis of peptide conjugates using dehydroalanines for chemoselective ligations

Y Zhu, WA Van Der Donk - Organic Letters, 2001 - ACS Publications
Protein and peptide conjugates such as glycopeptides, prenylated peptides, and
lipopeptides play essential roles in biology. A rapid and convergent entry into a variety of …

Orthogonal chemoselective assembly of hyaluronic acid networks and nanogels for drug delivery

D Ossipov, S Kootala, Z Yi, X Yang, J Hilborn - Macromolecules, 2013 - ACS Publications
Functionalization of hyaluronic acid (HA) with orthogonally reactive aldehyde and thiol
groups permitted simultaneous bioconjugation and networking/nanostructuring of the HA …

Synthesis of a New Heterobifunctional Linker, N-[4-(Aminooxy)butyl]maleimide, for Facile Access to a Thiol-Reactive 18F-Labeling Agent

T Toyokuni, JC Walsh, A Dominguez… - Bioconjugate …, 2003 - ACS Publications
A new heterobifunctional linker containing an aldehyde-reactive aminooxy group and a thiol-
reactive maleimide group, namely N-[4-(aminooxy) butyl] maleimide, was synthesized as a …

Tunable drug delivery using chemoselective functionalization of hydrogels

E Mauri, F Rossi, A Sacchetti - Materials Science and Engineering: C, 2016 - Elsevier
In the last decades interests on cleavable linkers are growing due to the need to develop
controlled drug delivery systems in biochemical and therapeutic applications. The synthesis …

Synthesis of an amphiphilic copolymer using biopolymer-dextran via a combination of ROP and RAFT techniques

PD Karmakar, S Pal - Polymer Chemistry, 2022 - pubs.rsc.org
Ring-opening polymerization (ROP) and reversible addition–fragmentation chain-transfer
(RAFT) polymerization are efficient synthetic approaches to develop self-assembled …

Incorporation of chemoselective functionalities into peptoids via solid-phase submonomer synthesis

T Horn, BC Lee, KA Dill… - Bioconjugate chemistry, 2004 - ACS Publications
A simple route to the introduction of a number of chemoselective functional groups into
peptoids (oligo (N-substituted glycines)) by an extension of the standard solid-phase …

Synthesis and biological activities of aryl-ether-, biaryl-, and fluorene-aspartic acid and diaminopropionic acid analogs as potent inhibitors of the high-affinity glutamate …

A Greenfield, C Grosanu, J Dunlop, B McIlvain… - Bioorganic & medicinal …, 2005 - Elsevier
Excitatory amino acid transporters (EAATs) play a pivotal role in maintaining glutamate
homeostasis in the mammalian central nervous system, with the EAAT-2 subtype thought to …

Site-specific incorporation of (aminooxy) acetic acid into proteins

BM Eisenhauer, SM Hecht - Biochemistry, 2002 - ACS Publications
By employing a general biosynthetic method for the elaboration of proteins containing
unnatural amino acid analogues, we incorporated (aminooxy) acetic acid into positions 10 …