Evolution is the hallmark of life. Descriptions of the evolution of microorganisms have
provided a wealth of information, but knowledge regarding “what happened” has precluded …

Salmonella enterica is a common foodborne illness in the United States and globally. An
increasing number of Salmonella infections are resistant to antibiotics, and many of the …

Plasmids can mediate horizontal gene transfer of antibiotic resistance, virulence genes, and
other adaptive factors across bacterial populations. Here, we analyze genomic composition …

Bacterial pathogens carrying multidrug resistance (MDR) plasmids are a major threat to
human health. The acquisition of antibiotic resistance genes (ARGs) in plasmids is often …

In Gram-negative bacteria, the insertion sequence IS 26 is highly active in disseminating
antibiotic resistance genes. IS 26 can recruit a gene or group of genes into the mobile gene …

Providencia stuartii is a member of the Morganellaceae family, notorious for its intrinsic
resistance to several antibiotics, including last-resort drugs such as colistin and tigecycline …

Non-typhoidal Salmonella remains a leading cause of foodborne illness in the United
States, with food animal products serving as a key conduit for transmission. The emergence …

Bacteria have evolved defence mechanisms against bacteriophages. Restriction-
modification systems provide innate immunity by degrading invading DNAs that lack proper …

The incidence and transmission of Klebsiella pneumoniae carbapenemase (KPC)
producing plasmids have been well documented. However, the evolutionary dynamics of …

While conducting genomic surveillance of carbapenemase-producing Enterobacteriaceae
(CPE) from patient colonisation and clinical infections at Birmingham's Queen Elizabeth …