Advances in modern osteotomies around the knee: report on the Association of Sports Traumatology, Arthroscopy, Orthopaedic surgery, Rehabilitation (ASTAOR) …

L Gao, H Madry, DV Chugaev, M Denti, A Frolov… - Journal of experimental …, 2019 - Springer
Corrective lower limb osteotomies are innovative and efficient therapeutic procedures for
restoring axial alignment and managing unicompartmental knee osteoarthritis. This review …

Post-traumatic knee osteoarthritis in the young patient: therapeutic dilemmas and emerging technologies

M Stiebel, LE Miller, JE Block - Open access journal of sports …, 2014 - Taylor & Francis
Traumatic knee injury is common in young adults and strongly contributes to premature
development of knee osteoarthritis (OA). Post-traumatic knee OA poses a therapeutic …

Lorecivivint, a novel Intraarticular CDC‐like kinase 2 and dual‐specificity tyrosine phosphorylation‐regulated kinase 1A inhibitor and Wnt pathway modulator for the …

Y Yazici, TE McAlindon, A Gibofsky… - Arthritis & …, 2020 - Wiley Online Library
Objective To assess the safety and efficacy of a novel Wnt pathway modulator, lorecivivint
(SM 04690), for treating pain and inhibiting structural progression in moderately to severely …

Clinical and economic burden of revision knee arthroplasty

M Bhandari, J Smith, LE Miller… - … Insights: Arthritis and …, 2012 - journals.sagepub.com
Surgery is indicated for symptomatic knee osteoarthritis (OA) when conservative measures
are unsuccessful. High tibial osteotomy (HTO), unicompartmental knee arthroplasty (UKA) …

[HTML][HTML] Quality of life in patients with knee osteoarthritis: a commentary on nonsurgical and surgical treatments

J Farr II, LE Miller, JE Block - The open orthopaedics journal, 2013 - ncbi.nlm.nih.gov
Knee osteoarthritis (OA) has a significant negative impact on health-related quality of life
(HRQoL). Identification of therapies that improve HRQoL in patients with knee OA may …

[HTML][HTML] Conservative management of symptomatic knee osteoarthritis: a flawed strategy?

DC Crawford, LE Miller, JE Block - Orthopedic reviews, 2013 - ncbi.nlm.nih.gov
Conservative management of medial compartment knee osteoarthritis (OA) is a misleading
term used to describe the application of medical, orthotic, and/or rehabilitative therapies …

A framework based on subject-specific musculoskeletal models and Monte Carlo simulations to personalize muscle coordination retraining

H Kainz, W Koller, E Wallnöfer, TR Bader… - Scientific Reports, 2024 - nature.com
Excessive loads at lower limb joints can lead to pain and degenerative diseases. Altering
joint loads with muscle coordination retraining might help to treat or prevent clinical …

Market positioning of remanufactured products with optimal planning for part upgrades

M Kwak, H Kim - Journal of Mechanical Design, 2013 - asmedigitalcollection.asme.org
In a market with rapid changes in technology and customer preferences, technological
obsolescence of end-of-life products poses a significant challenge to product recovery …

Evidence of cartilage repair by joint distraction in a canine model of osteoarthritis

K Wiegant, F Intema, PM van Roermund… - Arthritis & …, 2015 - Wiley Online Library
Objective Knee osteoarthritis (OA) is a degenerative joint disorder characterized by
cartilage, bone, and synovial tissue changes that lead to pain and functional impairment …

[HTML][HTML] Muscle recruitment strategies can reduce joint loading during level walking

B van Veen, E Montefiori, L Modenese, C Mazzà… - Journal of …, 2019 - Elsevier
Joint inflammation, with consequent cartilage damage and pain, typically reduces
functionality and affects activities of daily life in a variety of musculoskeletal diseases. Since …