Upon exhaustive research, the transdermal drug delivery system (TDDS) has appeared as a
potential, well-accepted, and popular approach to a novel drug delivery system. Ease of …

Transdermal drug administration has grown in popularity in the pharmaceutical research
community due to its potential to improve drug bioavailability, compliance among patients …

Injections into or through the skin are common drug or vaccine administration routes, which
can be achieved with conventional needles, microneedles, or needle-free jet injections …

Background Needle-free jet injection (NFJI) systems enable a controlled and targeted
delivery of drugs into skin tissue. However, a scarce understanding of their underlying …

The current state of commercially available needle-free liquid jet injectors for drug delivery
offers no way of controlling the output pressure of the device in real time, as the driving …

This study used numerical analysis to determine the transport phenomena of hot water
infiltration in a two-dimensional granular packed bed. The present study aims to investigate …

The development and characterisation of new drug delivery techniques often requires
visualising the location of delivered fluid in tissue samples. The opacity of tissue means that …

To reveal the penetration mechanism and present the penetration characteristics of high-
speed micro-jet with injection volume larger than 0.3 mL into soft tissue, the present study …

The needle-free injection is a new technique for treating subcutaneous drug delivery
through penetrating the skin with a high-speed liquid drug jet. The present study aims to …

The present thesis introduces a novel numerical framework for the study of bubble-tissue
interactions, crucial for understanding the mechanics behind tissue-induced damage in …