[HTML][HTML] IL-15 in T-cell responses and immunopathogenesis
IL-15 belongs to the common gamma chain cytokine family and has pleiotropic
immunological functions. IL-15 is a homeostatic cytokine essential for the development and …
immunological functions. IL-15 is a homeostatic cytokine essential for the development and …
NK-like CD8 T cell: one potential evolutionary continuum between adaptive memory and innate immunity
Q Wang, S Chen, Z Guo, S Xia… - Clinical and Experimental …, 2024 - academic.oup.com
SUMMARY CD8 T cells are crucial adaptive immune cells with cytotoxicity to fight against
pathogens or abnormal self-cells via major histocompatibility complex class I-dependent …
pathogens or abnormal self-cells via major histocompatibility complex class I-dependent …
Neutrophil-mediated hypoxia drives pathogenic CD8 T cell responses in cutaneous leishmaniasis
EA Fowler, CF Amorim, K Mostacada… - The Journal of …, 2024 - Am Soc Clin Investig
Cutaneous leishmaniasis caused by Leishmania parasites exhibits a wide range of clinical
manifestations. Although parasites influence disease severity, cytolytic CD8 T cell responses …
manifestations. Although parasites influence disease severity, cytolytic CD8 T cell responses …
CCR5 promotes the migration of pathological CD8+ T cells to the leishmanial lesions
L Amorim Sacramento, C Farias Amorim… - Plos …, 2024 - journals.plos.org
Cytolytic CD8+ T cells mediate immunopathology in cutaneous leishmaniasis without
controlling parasites. Here, we identify factors involved in CD8+ T cell migration to the lesion …
controlling parasites. Here, we identify factors involved in CD8+ T cell migration to the lesion …
NKG2C+ CD57+ natural killer cells with senescent features are induced during cutaneous leishmaniasis and accumulate in patients with lesional healing impairment
LP Covre, CH Fantecelle, AM Queiroz… - Clinical and …, 2024 - academic.oup.com
Natural killer (NK) cells include different subsets with diverse effector capacities that are
poorly understood in the context of parasitic diseases. Here, we investigated inhibitory and …
poorly understood in the context of parasitic diseases. Here, we investigated inhibitory and …
[HTML][HTML] CCR5 promotes the migration of CD8+ T cells to the leishmanial lesions
Cytolytic CD8+ T cells mediate immunopathology in cutaneous leishmaniasis without
controlling parasites. Here, we identify factors involved in CD8+ T cell migration to the lesion …
controlling parasites. Here, we identify factors involved in CD8+ T cell migration to the lesion …
CCR5 promotes the migration of CD8+ T cells to the leishmanial lesions
Cytolytic CD8+ T cells mediate immunopathology in cutaneous leishmaniasis without
controlling parasites. Here, we identify factors involved in CD8+ T cell migration to the lesion …
controlling parasites. Here, we identify factors involved in CD8+ T cell migration to the lesion …