Noncanonical functions of the autophagy machinery in pathways including LC3-associated
phagocytosis and LC3-associated endocytosis have garnered increasing interest in both …

Aspergillus fumigatus is a saprotrophic fungus; its primary habitat is the soil. In its ecological
niche, the fungus has learned how to adapt and proliferate in hostile environments. This …

Individuals suffering from severe viral respiratory tract infections have recently emerged as
“at risk” groups for developing invasive fungal infections. Influenza virus is one of the most …

Aspergillus fumigatus is an environmental filamentous fungus that can cause life-threatening
disease in immunocompromised individuals. The interactions between A. fumigatus and the …

Coronavirus disease 19 (COVID-19)-associated pulmonary aspergillosis (CAPA) is a severe
fungal infection complicating critically ill COVID-19 patients. Numerous retrospective and …

Background Influenza-associated pulmonary aspergillosis (IAPA) and COVID-19-associated
pulmonary aspergillosis (CAPA) affect about 15% of critically ill patients with influenza or …

Classically, canonical autophagy has been considered a survival mechanism initiated in
response to nutrient insufficiency. We now understand that autophagy functions in multiple …

Abstract LC3-associated phagocytosis (LAP) is a novel form of non-canonical autophagy
where LC3 (microtubule-associated protein 1A/1B–light chain 3) is conjugated to …

Respiratory fungal infection is a severe clinical problem, especially in patients with
compromised immune functions. Aspergillus, Cryptococcus, Pneumocystis, and endemic …

More than 90% of the cell wall of the filamentous fungus Aspergillus fumigatus comprises
polysaccharides. Biosynthesis of the cell wall polysaccharides is under the control of three …