Retinal biomarkers in Alzheimer's disease and mild cognitive impairment: A systematic review and meta-analysis
YJ Ge, W Xu, YN Ou, Y Qu, YH Ma, YY Huang… - Ageing Research …, 2021 - Elsevier
Background Retinal changes may reflect the pathophysiological processes in the central
nervous system and can be assessed by imaging modalities non-invasively. We aim to …
nervous system and can be assessed by imaging modalities non-invasively. We aim to …
Retinal vasculopathy in Alzheimer's disease
The retina has been increasingly investigated as a site of Alzheimer's disease (AD)
manifestation for over a decade. Early reports documented degeneration of retinal ganglion …
manifestation for over a decade. Early reports documented degeneration of retinal ganglion …
Retinal pathological features and proteome signatures of Alzheimer's disease
Alzheimer's disease (AD) pathologies were discovered in the accessible neurosensory
retina. However, their exact nature and topographical distribution, particularly in the early …
retina. However, their exact nature and topographical distribution, particularly in the early …
[HTML][HTML] Alzheimer's disease pathophysiology in the retina
The retina is an emerging CNS target for potential noninvasive diagnosis and tracking of
Alzheimer's disease (AD). Studies have identified the pathological hallmarks of AD …
Alzheimer's disease (AD). Studies have identified the pathological hallmarks of AD …
Müller cell degeneration and microglial dysfunction in the Alzheimer's retina
QA Xu, P Boerkoel, V Hirsch-Reinshagen… - Acta Neuropathologica …, 2022 - Springer
Amyloid beta (Aβ) deposits in the retina of the Alzheimer's disease (AD) eye may provide a
useful diagnostic biomarker for AD. This study focused on the relationship of Aβ with …
useful diagnostic biomarker for AD. This study focused on the relationship of Aβ with …
Role of retinal amyloid-β in neurodegenerative diseases: overlapping mechanisms and emerging clinical applications
Amyloid-β (Aβ) accumulations have been identified in the retina for neurodegeneration-
associated disorders like Alzheimer's disease (AD), glaucoma, and age-related macular …
associated disorders like Alzheimer's disease (AD), glaucoma, and age-related macular …
Advancements in materials, devices, and integration schemes for a new generation of neuromorphic computers
The slowing pace of performance improvements in modern processors along with the
breakdown of power scaling forecasts an imminent end to the traditional transistor scaling …
breakdown of power scaling forecasts an imminent end to the traditional transistor scaling …
Eye-tracking paradigms for the assessment of mild cognitive impairment: a systematic review
A Wolf, K Tripanpitak, S Umeda… - Frontiers in …, 2023 - frontiersin.org
Mild cognitive impairment (MCI), representing the 'transitional zone'between normal
cognition and dementia, has become a novel topic in clinical research. Although early …
cognition and dementia, has become a novel topic in clinical research. Although early …
Retinal capillary degeneration and blood-retinal barrier disruption in murine models of Alzheimer's disease
Extensive effort has been made studying retinal pathology in Alzheimer's disease (AD) to
improve early noninvasive diagnosis and treatment. Particularly relevant are vascular …
improve early noninvasive diagnosis and treatment. Particularly relevant are vascular …
Oxidative stress in the brain and retina after traumatic injury
The brain and the retina share many physiological similarities, which allows the retina to
serve as a model of CNS disease and disorder. In instances of trauma, the eye can even …
serve as a model of CNS disease and disorder. In instances of trauma, the eye can even …