Design of therapeutic biomaterials to control inflammation
Z Tu, Y Zhong, H Hu, D Shao, R Haag… - Nature Reviews …, 2022 - nature.com
Inflammation plays an important role in the response to danger signals arising from damage
to our body and in restoring homeostasis. Dysregulated inflammatory responses occur in …
to our body and in restoring homeostasis. Dysregulated inflammatory responses occur in …
Tailoring materials for modulation of macrophage fate
Human immune system acts as a pivotal role in the tissue homeostasis and disease
progression. Immunomodulatory biomaterials that can manipulate innate immunity and …
progression. Immunomodulatory biomaterials that can manipulate innate immunity and …
[HTML][HTML] A reactive oxygen species-responsive hydrogel encapsulated with bone marrow derived stem cells promotes repair and regeneration of spinal cord injury
Z Li, T Zhao, J Ding, H Gu, Q Wang, Y Wang, D Zhang… - Bioactive materials, 2023 - Elsevier
Spinal cord injury (SCI) is an overwhelming and incurable disabling event accompanied by
complicated inflammation-related pathological processes, such as excessive reactive …
complicated inflammation-related pathological processes, such as excessive reactive …
Engineered multifunctional zinc–organic framework-based aggregation-induced emission nanozyme for accelerating spinal cord injury recovery
Functional recovery following a spinal cord injury (SCI) is challenging. Traditional drug
therapies focus on the suppression of immune responses; however, strategies for alleviating …
therapies focus on the suppression of immune responses; however, strategies for alleviating …
Reactive oxygen species (ROS) scavenging biomaterials for anti-inflammatory diseases: From mechanism to therapy
J Liu, X Han, T Zhang, K Tian, Z Li, F Luo - Journal of Hematology & …, 2023 - Springer
Inflammation is a fundamental defensive response to harmful stimuli, but the overactivation
of inflammatory responses is associated with most human diseases. Reactive oxygen …
of inflammatory responses is associated with most human diseases. Reactive oxygen …
Inflammation: a target for treatment in spinal cord injury
X Freyermuth-Trujillo, JJ Segura-Uribe… - Cells, 2022 - mdpi.com
Spinal cord injury (SCI) is a significant cause of disability, and treatment alternatives that
generate beneficial outcomes and have no side effects are urgently needed. SCI may be …
generate beneficial outcomes and have no side effects are urgently needed. SCI may be …
Biocatalytic and antioxidant nanostructures for ROS scavenging and biotherapeutics
L Wang, B Zhu, Y Deng, T Li, Q Tian… - Advanced Functional …, 2021 - Wiley Online Library
In human systems, reactive oxygen species (ROS) significantly affect different physiological
activities and play critical roles in diverse living processes. It is widely known that excessive …
activities and play critical roles in diverse living processes. It is widely known that excessive …
Zinc‐modified sulfonated polyetheretherketone surface with immunomodulatory function for guiding cell fate and bone regeneration
The cytokines released by immune cells are considered important factors to induce bone
tissue regeneration. However, the pathway of those bone‐targeting macrophage cytokines …
tissue regeneration. However, the pathway of those bone‐targeting macrophage cytokines …
Materials roles for promoting angiogenesis in tissue regeneration
Enabling angiogenesis is critical for the success of tissue repair therapies and the fate of
tissue-engineered constructs. Although many biochemical signaling molecules have been …
tissue-engineered constructs. Although many biochemical signaling molecules have been …
Advances in biomaterial‐based spinal cord injury repair
Spinal cord injury (SCI) often leads to the loss of motor and sensory functions and is a major
challenge in neurological clinical practice. Understanding the pathophysiological changes …
challenge in neurological clinical practice. Understanding the pathophysiological changes …