A brief introduction to chemical reaction optimization
From the start of a synthetic chemist's training, experiments are conducted based on recipes
from textbooks and manuscripts that achieve clean reaction outcomes, allowing the scientist …
from textbooks and manuscripts that achieve clean reaction outcomes, allowing the scientist …
A field guide to flow chemistry for synthetic organic chemists
Flow chemistry has unlocked a world of possibilities for the synthetic community, but the idea
that it is a mysterious “black box” needs to go. In this review, we show that several of the …
that it is a mysterious “black box” needs to go. In this review, we show that several of the …
Automated solution-phase multiplicative synthesis of complex glycans up to a 1,080-mer
W Yao, DC Xiong, Y Yang, C Geng, Z Cong, F Li… - Nature …, 2022 - nature.com
Carbohydrates play essential roles in nature, such as in cell–cell communication, cell growth
and immunoresponse. However, the synthesis of structurally well-defined carbohydrates …
and immunoresponse. However, the synthesis of structurally well-defined carbohydrates …
[HTML][HTML] Scope of machine learning in materials research—A review
This comprehensive review investigates the multifaceted applications of machine learning in
materials research across six key dimensions, redefining the field's boundaries. It explains …
materials research across six key dimensions, redefining the field's boundaries. It explains …
Applications of Transmission Electron Microscopy in Phase Engineering of Nanomaterials
Phase engineering of nanomaterials (PEN) is an emerging field that aims to tailor the
physicochemical properties of nanomaterials by precisely manipulating their crystal phases …
physicochemical properties of nanomaterials by precisely manipulating their crystal phases …
Evolving scenario of big data and Artificial Intelligence (AI) in drug discovery
MK Tripathi, A Nath, TP Singh, AS Ethayathulla… - Molecular Diversity, 2021 - Springer
The accumulation of massive data in the plethora of Cheminformatics databases has made
the role of big data and artificial intelligence (AI) indispensable in drug design. This has …
the role of big data and artificial intelligence (AI) indispensable in drug design. This has …
Analytical tools integrated in continuous-flow reactors: which one for what?
M Rodriguez-Zubiri, FX Felpin - Organic Process Research & …, 2022 - ACS Publications
The concept and practices of chemical synthesis are being profoundly transformed toward
the development of fully autonomous continuous processes. Critical to the development of …
the development of fully autonomous continuous processes. Critical to the development of …
Towards 4th industrial revolution efficient and sustainable continuous flow manufacturing of active pharmaceutical ingredients
CR Sagandira, S Nqeketo, K Mhlana, T Sonti… - Reaction Chemistry & …, 2022 - pubs.rsc.org
Continuous flow chemistry has opened a new paradigm in both the laboratory and
pharmaceutical industry. This review details the recently reported literature on continuous …
pharmaceutical industry. This review details the recently reported literature on continuous …
Will the next generation of chemical plants be in miniaturized flow reactors?
JCM Monbaliu, J Legros - Lab on a Chip, 2023 - pubs.rsc.org
For decades, a production paradigm based on centralized, stepwise, large scale processes
has dominated the chemical industry horizon. While effective to meet an ever increasing …
has dominated the chemical industry horizon. While effective to meet an ever increasing …
Forgotten and forbidden chemical reactions revitalised through continuous flow technology
A Bonner, A Loftus, AC Padgham… - Organic & Biomolecular …, 2021 - pubs.rsc.org
Continuous flow technology has played an undeniable role in enabling modern chemical
synthesis, whereby a myriad of reactions can now be performed with greater efficiency …
synthesis, whereby a myriad of reactions can now be performed with greater efficiency …