[HTML][HTML] Recent preclinical and clinical progress in liposomal doxorubicin
Doxorubicin (DOX) is a potent anti-cancer agent that has garnered great interest in research
due to its high efficacy despite dose-limiting toxicities. Several strategies have been …
due to its high efficacy despite dose-limiting toxicities. Several strategies have been …
Development of “smart” drug delivery systems for chemo/PDT synergistic treatment
M Yu, R Cao, Z Ma, M Zhu - Journal of Materials Chemistry B, 2023 - pubs.rsc.org
Although chemotherapy and photodynamic therapy (PDT) have been developed for fighting
cancer, the complex and heterogeneous nature of tumors makes it difficult for a single …
cancer, the complex and heterogeneous nature of tumors makes it difficult for a single …
[HTML][HTML] Nanomaterials in cancer: Reviewing the combination of hyperthermia and triggered chemotherapy
TP Ribeiro, JA Moreira, FJ Monteiro… - Journal of controlled …, 2022 - Elsevier
Nanoparticle mediated hyperthermia has been explored as a method to increase cancer
treatment efficacy by heating tumours inside-out. With that purpose, nanoparticles have …
treatment efficacy by heating tumours inside-out. With that purpose, nanoparticles have …
Forcing the antitumor effects of HSPs using a modulated electric field
CA Minnaar, A Szasz - Cells, 2022 - mdpi.com
The role of Heat Shock Proteins (HSPs) is a “double-edged sword” with regards to tumors.
The location and interactions of HSPs determine their pro-or antitumor activity. The present …
The location and interactions of HSPs determine their pro-or antitumor activity. The present …
Heat shock factor 1 inhibition enhances the effects of modulated electro hyperthermia in a triple negative breast cancer mouse model
Female breast cancer is the most diagnosed cancer worldwide. Triple negative breast
cancer (TNBC) is the most aggressive type and there is no existing endocrine or targeted …
cancer (TNBC) is the most aggressive type and there is no existing endocrine or targeted …
[HTML][HTML] Targeting the heat shock response induced by modulated electro-hyperthermia (mEHT) in cancer
Abstract The Heat Shock Response (HSR) is a cellular stress reaction crucial for cell survival
against stressors, including heat, in both healthy and cancer cells. Modulated electro …
against stressors, including heat, in both healthy and cancer cells. Modulated electro …
Enhancing therapeutic efficacy in triple‐negative breast cancer and melanoma: synergistic effects of modulated electro‐hyperthermia (mEHT) with NSAIDs especially …
N Giunashvili, JM Thomas, CA Schvarcz… - Molecular …, 2024 - Wiley Online Library
Triple‐negative breast cancer (TNBC) is a leading cause of cancer mortality and lacks
modern therapy options. Modulated electro‐hyperthermia (mEHT) is an adjuvant therapy …
modern therapy options. Modulated electro‐hyperthermia (mEHT) is an adjuvant therapy …
Non-thermal membrane effects of electromagnetic fields and therapeutic applications in oncology
P Wust, U Stein, P Ghadjar - International Journal of Hyperthermia, 2021 - Taylor & Francis
The temperature-independent effects of electromagnetic fields (EMF) have been
controversial for decades. Here, we critically analyze the available literature on non-thermal …
controversial for decades. Here, we critically analyze the available literature on non-thermal …
External basic hyperthermia devices for preclinical studies in small animals
MI Priester, S Curto, GC van Rhoon, TLM Ten Hagen - Cancers, 2021 - mdpi.com
Simple Summary The application of mild hyperthermia can be beneficial for solid tumor
treatment by induction of sublethal effects on a tissue-and cellular level. When designing a …
treatment by induction of sublethal effects on a tissue-and cellular level. When designing a …
Digoxin-Mediated Inhibition of Potential Hypoxia-Related Angiogenic Repair in Modulated Electro-Hyperthermia (mEHT)-Treated Murine Triple-Negative Breast …
SMZ Bokhari, K Aloss, PH Leroy Viana… - ACS Pharmacology & …, 2024 - ACS Publications
Triple-negative breast cancer (TNBC) is a highly aggressive breast cancer type with no
targeted therapy and hence limited treatment options. Modulated electrohyperthermia …
targeted therapy and hence limited treatment options. Modulated electrohyperthermia …