Ulcerative colitis (UC) and Crohn's disease (CD) are part of Inflammatory Bowel Diseases
(IBD) and have pathophysiological processes such as bowel necrosis and enteric neurons …

Different glial cell types are found throughout the central (CNS) and peripheral nervous
system (PNS), where they have important functions. These cell types are also involved in …

The high turnover and regenerative capacity of the adult intestine relies on resident stem
cells located at the bottom of the crypt. The enteric nervous system consists of an abundant …

Highlights•Enteric glial cells (EGCs) are required for maintenance of gut tissue
homeostasis.•GFAP+ EGCs regulate the health of the intestinal epithelial barrier.•EGCs …

Periodontitis is considered a non-communicable chronic disease caused by a dysbiotic
microbiota, which generates a low-grade systemic inflammation that chronically damages …

Inflammatory bowel diseases (IBD) such as Crohn's disease (CD) and Ulcerative colitis (UC)
have a complex and multifactorial pathogenesis which is incompletely understood. A typical …

The gastrointestinal tract is innervated by the enteric nervous system (ENS), a complex
network of neurons and glial cells, also called the “second brain”. Enteric glial cells, one of …

Chronic inflammation is linked to carcinogenesis, particularly in the digestive organs, ie, the
stomach, colon, and liver. The mechanism of this effect has, however, only partly been …

The dense innervation of the gastro-intestinal tract with neuronal networks, which are in
close proximity to immune cells, implies a pivotal role of neurons in modulating immune …

Ethnopharmacological relevance Ulcerative colitis (UC) is a relapsing inflammatory disease
that still demands for effective remedies due to various adverse effects of the current …