Breast cancer

N Harbeck, F Penault-Llorca… - Nature reviews …, 2019 - mayoclinic.elsevierpure.com
Breast cancer is the most frequent malignancy in women worldwide and is curable in~ 70–
80% of patients with early-stage, non-metastatic disease. Advanced breast cancer with …

Molecular classification of breast cancer

JYS Tsang, MT Gary - Advances in anatomic pathology, 2020 - journals.lww.com
Cancer classification aims to provide an accurate diagnosis of the disease and prediction of
tumor behavior to facilitate oncologic decision making. Traditional breast cancer …

Breast cancer: a molecularly heterogenous disease needing subtype-specific treatments

U Testa, G Castelli, E Pelosi - Medical Sciences, 2020 - mdpi.com
Breast cancer is the most commonly occurring cancer in women. There were over two-
million new cases in world in 2018. It is the second leading cause of death from cancer in …

A comprehensive overview of metaplastic breast cancer: clinical features and molecular aberrations

TP Reddy, RR Rosato, X Li, S Moulder… - Breast Cancer …, 2020 - Springer
Metaplastic breast cancer (MpBC) is an exceedingly rare breast cancer variant that is
therapeutically challenging and aggressive. MpBC is defined by the histological presence of …

Germline pathogenic variants in metaplastic breast cancer patients and the emerging role of the BRCA1 gene

G Corso, M Marabelli, M Calvello, S Gandini… - European Journal of …, 2023 - nature.com
Metaplastic breast cancer (MpBC) is a rare, aggressive breast cancer (BC) histotype. Scarce
information is available about MpBC genetic predisposition. Previous studies, mainly …

[HTML][HTML] Breast tumor-on-chip models: From disease modeling to personalized drug screening

B Subia, UR Dahiya, S Mishra, J Ayache… - Journal of Controlled …, 2021 - Elsevier
Breast cancer is one of the leading causes of mortality worldwide being the most common
cancer among women. Despite the significant progress obtained during the past years in the …

Collective metastasis: coordinating the multicellular voyage

E Wrenn, Y Huang, K Cheung - Clinical & experimental metastasis, 2021 - Springer
The metastatic process is arduous. Cancer cells must escape the confines of the primary
tumor, make their way into and travel through the circulation, then survive and proliferate in …

Spindle cell lesions of the breast: a diagnostic approach

EA Rakha, E Brogi, I Castellano, C Quinn - Virchows Archiv, 2022 - Springer
Spindle cell lesions of the breast comprise a heterogeneous group of lesions, ranging from
reactive and benign processes to aggressive malignant tumours. Despite their rarity, they …

Molecular features of metaplastic breast carcinoma: an infrequent subtype of triple negative breast carcinoma

S González-Martínez, B Pérez-Mies, I Carretero-Barrio… - Cancers, 2020 - mdpi.com
Metaplastic breast carcinoma (MBC) is a heterogeneous group of infrequent invasive
carcinomas that display differentiation of the neoplastic epithelium towards squamous cells …

Metaplastic breast cancers frequently express immune checkpoint markers FOXP3 and PD-L1

E Kalaw, M Lim, JR Kutasovic, A Sokolova… - British Journal of …, 2020 - nature.com
Background Metaplastic breast carcinoma encompasses a heterogeneous group of tumours
with differentiation into squamous and/or spindle, chondroid, osseous or rhabdoid …