A single-cell and spatial RNA-seq database for Alzheimer's disease (ssREAD)

C Wang, D Acosta, M McNutt, J Bian, A Ma… - Nature …, 2024 - nature.com
Alzheimer's Disease (AD) pathology has been increasingly explored through single-cell and
single-nucleus RNA-sequencing (scRNA-seq & snRNA-seq) and spatial transcriptomics …

ssREAD: A Single-cell and Spatial RNA-seq Database for Alzheimer's Disease

C Wang, M McNutt, A Ma, H Fu, Q Ma - bioRxiv, 2023 - biorxiv.org
Alzheimer's Disease (AD) is a neurodegenerative malady predominantly affecting the
elderly and exhibits its debilitating effects on a dementia-prone population. Recently, the …

Genes Selectively Expressed in Rat Organs

D Li, X Wan, Y Yun, Y Li, W Duan - Current Genomics, 2024 - benthamdirect.com
Background: Understanding organic functions at a molecular level is important for scientists
to unveil the disease mechanism and to develop diagnostic or therapeutic methods. Aims …

[HTML][HTML] MntJULiP and Jutils: Differential splicing analysis of RNA-seq data with covariates

WW Lui, G Yang, L Florea - bioRxiv, 2024 - ncbi.nlm.nih.gov
Differences in alternative splicing patterns can reveal important markers of phenotypic
differentiation, including biomarkers of disease. Emerging large and complex RNA-seq …

Using an in-vivo Drosophila model to determine the influence of age and hyperphosphorylated tau on neuronal structure and function

B Richardson - 2024 - eprints.soton.ac.uk
Although ageing is considered the leading risk factor for Alzheimer's Disease (AD),
knowledge of what occurs to neuronal morphology and cytoskeletal structures during …