The field of nutritional psychiatry has generated observational and efficacy data supporting a
role for healthy dietary patterns in depression onset and symptom management. To guide …

BackgroundPeripheral low-grade inflammation in depression is increasingly seen as a
therapeutic target. We aimed to establish the prevalence of low-grade inflammation in …

Introduction: There has long been an interest in the effects of diet on mental health, and the
interaction of the two with stress; however, the nature of these relationships is not well …

Does it matter what we eat for our mental health? Accumulating data suggests that this may
indeed be the case and that diet and nutrition are not only critical for human physiology and …

We conducted this meta-analysis of double-blind randomized placebo-controlled trials to
estimate the efficacy of omega-3 polyunsaturated fatty acids (PUFAs), especially …

Eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) can exert antidepressant,
anti-inflammatory and neuroprotective properties, but the exact molecular mechanism …

Peripheral blood C-reactive protein (CRP) is a biomarker used clinically to measure
systemic inflammation and is reproducibly increased in a subset of patients with major …

Classically, polyunsaturated fatty acids (PUFA) were largely thought to be relatively inert
structural components of brain, largely important for the formation of cellular membranes …

Objectives The therapeutic use of nutrient-based 'nutraceuticals' and plant-based
'phytoceuticals' for the treatment of mental disorders is common; however, despite recent …

Depression and inflammation fuel one another. Inflammation plays a key role in
depression's pathogenesis for a subset of depressed individuals; depression also primes …