A review on the development of bacterial multi-epitope recombinant protein vaccines via reverse vaccinology
Y Li, MHR Farhan, X Yang, Y Guo, Y Sui, J Chu… - International Journal of …, 2024 - Elsevier
Bacterial vaccines play a crucial role in combating bacterial infectious diseases. Apart from
the prevention of disease, bacterial vaccines also help to reduce the mortality rates in …
the prevention of disease, bacterial vaccines also help to reduce the mortality rates in …
In-silico design and evaluation of an epitope-based serotype-independent promising vaccine candidate for highly cross-reactive regions of pneumococcal surface …
E Afshari, RA Cohan… - Journal of Translational …, 2023 - Springer
Background The pathogenicity of pneumococcus with high morbidity, mortality, and multi-
drug resistance patterns has been increasing. The limited coverage of the licensed …
drug resistance patterns has been increasing. The limited coverage of the licensed …
Proteomic profiling of membrane vesicles from Mycobacterium avium subsp. paratuberculosis: Navigating towards an in silico design of a multi-epitope vaccine …
Bacteria typically produce membrane vesicles (MVs) at varying levels depending on the
surrounding environments. Gram-negative bacterial outer membrane vesicles (OMVs) have …
surrounding environments. Gram-negative bacterial outer membrane vesicles (OMVs) have …
A comprehensive immunoinformatic analysis of chitin deacetylase's and MP88 for designing multi-epitope vaccines against Cryptococcus neoformans
Cryptococcus neoformans causes life-threatening pneumonia and meningitis and is
regarded as one of the leading killers of immunocompromised individuals. There is currently …
regarded as one of the leading killers of immunocompromised individuals. There is currently …
De novo identification of bacterial antigens of a clinical isolate by combining use of proteosurfaceomics, secretomics, and BacScan technologies
J Yang, X Zhang, J Dong, Q Zhang, E Sun… - Frontiers in …, 2023 - frontiersin.org
Background Emerging infectious diseases pose a significant threat to both human and
animal populations. Rapid de novo identification of protective antigens from a clinical isolate …
animal populations. Rapid de novo identification of protective antigens from a clinical isolate …
Design of a novel multiepitope vaccine against Chlamydia pneumoniae using the extracellular protein as a target
X Guo, X Pan, Q Sun, Y Hu, J Shi - Scientific Reports, 2023 - nature.com
Chlamydia pneumoniae (C. pneumoniae) infection in humans is universal and causes
various respiratory infectious diseases, making a safe and effective preventive vaccine …
various respiratory infectious diseases, making a safe and effective preventive vaccine …
Novel dual-pathogen multi-epitope mRNA vaccine development for Brucella melitensis and Mycobacterium tuberculosis in silico approach
Y Zhu, J Shi, Q Wang, Y Zhu, M Li, T Tian, H Shi… - Plos one, 2024 - journals.plos.org
Brucellosis and Tuberculosis, both of which are contagious diseases, have presented
significant challenges to global public health security in recent years. Delayed treatment can …
significant challenges to global public health security in recent years. Delayed treatment can …
Immunoinformatics Approach to Design a Chimeric CD70‐Peptide Vaccine against Renal Cell Carcinoma
H Namdari, F Rezaei, F Heidarnejad… - Journal of …, 2024 - Wiley Online Library
Renal cell carcinoma (RCC) accounts for the majority of cancer‐related deaths worldwide.
Overexpression of CD70 has been linked to advanced stages of RCC. Therefore, this study …
Overexpression of CD70 has been linked to advanced stages of RCC. Therefore, this study …