L-selectin (CD62L) is a type-I transmembrane glycoprotein and cell adhesion molecule that
is expressed on most circulating leukocytes. Since its identification in 1983, L-selectin has …

Resident memory T (Trm) cells stably occupy tissues and cannot be sampled in superficial
venous blood. Trm cells are heterogeneous but collectively constitute the most abundant …

The human immune system displays substantial variation between individuals, leading to
differences in susceptibility to autoimmune disease. We present single-cell RNA sequencing …

Vascular endothelium offers a variety of therapeutic targets for the treatment of cancer,
cardiovascular diseases, inflammation, and oxidative stress. Significant research has been …

T cells function locally. Accordingly, T cells' recognition of antigen, their subsequent
activation and differentiation, and their role in the processes of infection control, tumour …

Can an abundantly expressed molecule be a reliable marker for the cancer-initiating cells
(CICs; also known as cancer stem cells), which constitute the minority of cells within the …

A fraction of mature T cells can be activated by peripheral self-antigens, potentially eliciting
host autoimmunity. We investigated homeostatic control of self-activated T cells within …

Multiple protein families, each with a distinct function, provide the traffic signals for
leukocytes. The selectin family of adhesion molecules (Figure 2) has an N-terminal domain …

A comment on this article appears in" Algorithm for immunophenotyping of low-grade B
lymphomas." Blood. 1996 Sep 15; 88 (6): 2361-2. A comment on this article appears in" …

EXPERIMENTAL autoimmune encephalomyelitis (EAE) is an inflammatory condition of the
central nervous system with similarities to multiple sclerosis1, 2. In both diseases, circulating …