Cancer is still one of the most widespread diseases globally, it is considered a vital health
challenge worldwide and one of the main barriers to long life expectancy. Due to the …

Many flavonoids, as eminent phenolic compounds, have been commercialized and
consumed as dietary supplements due to their incredible human health benefits. In the …

Resistance to 5-Fluorouracil (5-Fu) chemotherapy is the main cause of treatment failure in
the cure of colon cancer. Therefore, there is an urgent need to explore a safe and effective …

With cancer incidence rates continuing to increase and occurrence of resistance in drug
treatment, there is a pressing demand to find safer and more effective anticancer strategy for …

Colorectal (CRC) and gastric cancers (GC) are the most common digestive tract cancers
with a high incidence rate worldwide. The current treatment including surgery …

Drug resistance is still an obstacle in cancer therapy, leading to the failure of tumor
treatment. The emergence of tumor drug resistance has always been a main concern of …

Lansium domesticum (Langsat, Meliaceae) is a tropical fruit mainly found in Southeast Asian
countries, particularly in Thailand, Malaysia, Indonesia, and the Philippines. Traditionally, it …

Pharmacoresistance of cancer cells to many drugs used in chemotherapy remains a major
challenge for the treatment of cancer. Multidrug resistance transporters, especially ATP …

Simple Summary This review explores the challenges of drug resistance in cancer treatment
and discusses innovative strategies to overcome them. Researchers aim to understand how …

Chrysin (CHR), a dihydroxy flavone, exhibits several bioactivities, ie, anti-oxidant, anti-
inflammatory, and anti-cancer, and is known to possess limited aqueous solubility causing …