About 10 distinct potassium channels in the heart are involved in shaping the action
potential. Some of the K+ channels are primarily responsible for early repolarization …

Atrial fibrillation (AF) is of public health importance and profoundly increases morbidity,
mortality, and healthrelated expenditures. Morbidities include the increased risks of …

Small-conductance Ca2+-activated K+ (SK) channels mediate neuron excitability and are
associated with synaptic transmission and plasticity. They also regulate immune responses …

Over the last decade, mouse models have become a popular instrument for studying cardiac
arrhythmias. This review assesses in which respects a mouse heart is a miniature human …

Within the potassium ion channel family, calcium activated potassium (KCa) channels are
unique in their ability to couple intracellular Ca2+ signals to membrane potential variations …

Aims Small-conductance calcium-activated potassium (SK) channels are expressed in the
heart of various species, including humans. The aim of the present study was to address …

Background—Recent evidence points to functional Ca2+-dependent K+ (SK) channels in
the heart that may govern atrial fibrillation (AF) risk, but the underlying mechanisms are …

Small-and intermediate-conductance Ca2+-activated K+ (KCa2. x/KCa3. 1 also called
SK/IK) channels are gated exclusively by intracellular Ca2+. The Ca2+ binding protein …

The exceptional versatility of calmodulin (CaM) three-dimensional arrangement is reflected
in the growing number of structural models of CaM/protein complexes currently available in …

Small conductance calcium-activated potassium (SK2/K Ca 2.2) channels are known to be
located in the neuronal plasma membrane where they provide feedback control of NMDA …