Imaging can take many forms—from optical microscopes and telescopes through
ultrasonography to X-ray tomography. However, regardless of the imaging modality, the …

Optical imaging has had a central role in elucidating the underlying biological and
physiological mechanisms in living specimens owing to its high spatial resolution, molecular …

The last decade has seen the development of a wide set of tools, such as wavefront
shaping, computational or fundamental methods, that allow us to understand and control …

In the field of biomedical optics, optical scattering has traditionally limited the range of
imaging within tissue to a depth of one millimetre. A recently developed class of wavefront …

Due to the highly inhomogeneous distributions of refractive indexes, light propagation in
complex media such as biological tissue experiences multiple light scattering events. The …

Optical wavefront shaping has emerged as a powerful tool for manipulating light in strongly
scattering media. It enables diffraction-limited focusing and imaging at depths where …

Focusing light deep inside living tissue has not been achieved despite its promise to play a
central role in biomedical imaging, optical manipulation and therapy. To address this …

Focusing of light in the diffusive regime inside scattering media has long been considered
impossible. Recently, this limitation has been overcome with time reversal of ultrasound …

Wavefront shaping based on digital optical phase conjugation (DOPC) focuses light through
or inside scattering media, but the low speed of DOPC prevents it from being applied to …

Multiphoton microscopy is the current method of choice for in vivo deep-tissue imaging. The
long laser wavelength suffers less scattering, and the 3D-confined excitation permits the use …