A conserved signalling cascade—termed the mitotic-exit network in budding yeast and the
septation-initiation network in fission yeast—controls key events during exit from mitosis and …

Cytokinesis is the final event of the cell division cycle, and its completion results in
irreversible partition of a mother cell into two daughter cells. Cytokinesis was one of the first …

Bfa1p and Bub2p are spindle checkpoint proteins that likely have GTPase activation activity
and are associated with the budding yeast spindle pole body (SPB). Here, we show that …

Centrosomes, spindle pole bodies, and related structures in other organisms are a
morphologically diverse group of organelles that share a common ability to nucleate and …

Background: Both symmetric and asymmetric cell divisions are required for the generation of
appropriate cell lineages during development. Wild-type Schizosaccharomyces pombe cells …

Unlike ubiquitin, the ubiquitin-like protein modifier SUMO-1 and its budding yeast
homologue Smt3p have been shown to be more important for posttranslational protein …

Proper completion of mitosis requires careful coordination of numerous cellular events. It is
crucial, for example, that cells do not initiate spindle disassembly and cytokinesis until …

Schizosaccharomyces pombe cells divide by medial fission throughout contraction of an
actomyosin ring and deposition of a multilayered division septum that must be cleaved to …

The molecular mechanisms by which the endosomal sorting complexes required for
transport (ESCRT) proteins contribute to the integrity of the nuclear envelope (NE) barrier …

Inactivation of mitotic cyclin-dependent kinases (Cdks) is required for cells to exit mitosis [1,
2]. In the budding yeast Saccharomyces cerevisiae, Cdk inactivation is triggered by the …