After induction and specification in the ectoderm, at the border of the neural plate, the neural
crest (NC) population leaves its original territory through a delamination process. Soon …

The efficacy of macrophage-mediated inflammatory response relies on the coordinated
expression of key factors, which expression is finely regulated at both transcriptional and …

Abstract Development and progression of cancer are mediated by alterations in
transcriptional networks, resulting in a disturbed balance between the activity of oncogenes …

Objective—MicroRNA plays important roles in vascular biology, but the regulation of
endothelial-specific microRNA is not well characterized. MicroRNA-126 (miR-126) is highly …

The E26 transformation-specific (ETS) family of transcription factors is critical for
development, differentiation, proliferation and also has a role in apoptosis and tissue …

Ets factors are members of one of the largest families of evolutionarily conserved
transcription factors, regulating critical functions in normal cell homeostasis, which when …

Tumor-associated macrophages (TAM) are implicated in breast cancer metastasis, but
relatively little is known about the underlying genes and pathways that are involved. The …

Nitric oxide (NO) is a ubiquitous, endogenously produced, water-soluble signaling molecule
playing critical roles in physiological processes. Nitric oxide plays pleiotropic roles in cancer …

Background Gene expression signatures are typically identified by correlating gene
expression patterns to a disease phenotype of interest. However, individual gene-based …

Abstract Introduction The Ets-1 transcription factor is a candidate breast cancer oncogene
that regulates the expression of genes involved in tumor progression and metastasis. Ets-1 …