Astrocytes are neural cells of ectodermal, neuroepithelial origin that provide for homeostasis
and defense of the central nervous system (CNS). Astrocytes are highly heterogeneous in …

There is increasing knowledge regarding the role of the microbiome in modulating brain and
behaviour. Indeed, the actions of microbial metabolites are key for appropriate gut-brain …

The hypothalamus is a central regulator of many innate behaviors essential for survival, but
the molecular mechanisms controlling hypothalamic patterning and cell fate specification …

Astrocytes are key homeostatic regulators in the central nervous system and play important
roles in physiology. After brain damage caused by eg, status epilepticus, traumatic brain …

Obesity, type 2 diabetes, and their associated comorbidities impact brain metabolism and
function and constitute risk factors for cognitive impairment. Alterations to taurine …

Cytotoxic brain edema triggered by neuronal swelling is the chief cause of mortality
following brain trauma and cerebral infarct. Using fluorescence lifetime imaging to analyze …

Cells need to regulate their volume to counteract osmotic swelling or shrinkage, as well as
during cell division, growth, migration and cell death. Mammalian cells adjust their volume …

Background Glial cells of the central nervous system directly influence neuronal activity by
releasing neuroactive small molecules, including glutamate. Long-lasting cocaine-induced …

Psoralen is the principal bioactive component in the dried fruits of Cullen corylifolium (L.)
Medik (syn. Psoralea corylifolia L), termed “Buguzhi” in traditional Chinese medicine (TCM) …

Water intake is one of the most basic physiological responses and is essential to sustain life.
The perception of thirst has a critical role in controlling body fluid homeostasis and if …