Strategy to targeting the immune resistance and novel therapy in colorectal cancer

W Gang, JJ Wang, R Guan, S Yan, F Shi… - Cancer …, 2018 - Wiley Online Library
Assessing the CRC subtypes that can predict the outcome of colorectal cancer (CRC) in
patients with immunogenicity seems to be a promising strategy to develop new drugs that …

Resveratrol inhibits IL‐6‐induced ovarian cancer cell migration through epigenetic up‐regulation of autophagy

A Ferraresi, S Phadngam, F Morani… - Molecular …, 2017 - Wiley Online Library
Interleukin‐6 (IL‐6), a pro‐inflammatory cytokine released by cancer‐associated fibroblasts,
has been linked to the invasive and metastatic behavior of ovarian cancer cells. Resveratrol …

MINT: a multivariate integrative method to identify reproducible molecular signatures across independent experiments and platforms

F Rohart, A Eslami, N Matigian, S Bougeard… - BMC …, 2017 - Springer
Background Molecular signatures identified from high-throughput transcriptomic studies
often have poor reliability and fail to reproduce across studies. One solution is to combine …

A survey of transcripts generated by spinal muscular atrophy genes

NN Singh, EW Ottesen, RN Singh - Biochimica et Biophysica Acta (BBA) …, 2020 - Elsevier
Abstract Human Survival Motor Neuron (SMN) genes code for SMN, an essential
multifunctional protein. Complete loss of SMN is embryonic lethal, while low levels of SMN …

cMyc regulates the size of the premigratory neural crest stem cell pool

L Kerosuo, ME Bronner - Cell reports, 2016 - cell.com
The neural crest is a transient embryonic population that originates within the central
nervous system (CNS) and then migrates into the periphery and differentiates into multiple …

Glutaminase isoforms expression switches microRNA levels and oxidative status in glioblastoma cells

J de Los Santos-Jiménez… - Journal of biomedical …, 2021 - Springer
Background Glutaminase isoenzymes GLS and GLS2 play apparently opposing roles in
cancer: GLS acts as an oncoprotein, while GLS2 (GAB isoform) has context specific tumour …

Acquired genetic alterations in tumor cells dictate the development of high-risk neuroblastoma and clinical outcomes

FH Khan, V Pandian, S Ramraj, M Natarajan… - BMC cancer, 2015 - Springer
Background Determining the driving factors and molecular flow-through that define the
switch from favorable to aggressive high-risk disease is critical to the betterment of …

[HTML][HTML] Production of levan from Bacillus subtilis var. natto and apoptotic effect on SH-SY5Y neuroblastoma cells

AM Vieira, F Zahed, AC Crispim, E de Souza Bento… - Carbohydrate …, 2021 - Elsevier
Levan is a high-valued polysaccharide of fructose produced by several microbial species.
These polysaccharides have been described as effective therapeutic agents in some human …

An engineered Prussian blue nanoparticles‐based nanoimmunotherapy elicits robust and persistent immunological memory in a TH‐MYCN neuroblastoma model

A Shukla, J Cano-Mejia, J Andricovich… - Advanced …, 2021 - Wiley Online Library
A combination therapy using Prussian blue nanoparticles (PBNP) as photothermal therapy
(PTT) agents coated with CpG oligodeoxynucleotides, an immunologic adjuvant, as a …

MicroRNA miR-93-5p regulates expression of IL-8 and VEGF in neuroblastoma SK-N-AS cells

E Fabbri, G Montagner, N Bianchi… - Oncology …, 2016 - spandidos-publications.com
The role of the microRNA miR-93-5p on the secretome profile and the expression levels of
vascular endothelial growth factor (VEGF) and interleukin-8 (IL-8) was investigated in the …