Approximately 33% of melanomas are derived directly from benign, melanocytic nevi.
Despite this, the vast majority of melanocytic nevi, which typically form as a result of BRAF …

ContextThe incidence of cutaneous melanoma has increased over the past several
decades, making its early diagnosis a continuing public health priority. The ABCD …

BACKGROUND: Early detection of melanoma is the best way to improve prognosis. Digital
follow-up (DFU) programs of populations at high risk could be an efficient strategy for …

Given its propensity to metastasize and the lack of effective therapies for most patients with
advanced disease, early detection of melanoma is a clinical imperative. Although there are …

Cancer stem cells (CSC) have been identified in hematological malignancies and several
solid cancers. Similar to physiological stem cells, CSC are capable of self‐renewal and …

In the past 5 years, there have been notable strides toward the earlier recognition and
discovery of melanoma, including new technologies to complement and augment the clinical …

THE PUBLIC HEALTH IMPACT OF MALIGNANT melanoma continues to increase. It has
been estimated that 59 580 newly diagnosed cases of invasive melanoma and an additional …

Objective To compare dermoscopic features of melanocytic nevi with those of early
melanomas that were not excised initially because of their uncharacteristic clinical and …

Since its description in the 1970s, the dysplastic nevus has been a source of confusion, and
whether it represents a precursor to melanoma remains a controversial subject. Although a …

Stem cells play a critical role in normal tissue maintenance, and mutations in these stem
cells may give rise to cancer. We hypothesize that melanoma develops from a mutated stem …