Niosome: A promising nanocarrier for natural drug delivery through blood‐brain barrier

M Gharbavi, J Amani, H Kheiri-Manjili… - Advances in …, 2018 - Wiley Online Library
Niosomes (the nonionic surfactant vesicles), considered as novel drug delivery systems, can
improve the solubility and stability of natural pharmaceutical molecules. They are …

Direct nose to brain drug delivery via integrated nerve pathways bypassing the blood–brain barrier: an excellent platform for brain targeting

CV Pardeshi, VS Belgamwar - Expert opinion on drug delivery, 2013 - Taylor & Francis
Introduction: The blood–brain barrier (BBB) represents a stringent barrier for delivery of
neurotherapeutics in vivo. An attempt to overcome this barrier is represented by the direct …

[HTML][HTML] Intranasal delivery of nanoformulations: a potential way of treatment for neurological disorders

SU Islam, A Shehzad, MB Ahmed, YS Lee - Molecules, 2020 - mdpi.com
Although the global prevalence of neurological disorders such as Parkinson's disease,
Alzheimer's disease, glioblastoma, epilepsy, and multiple sclerosis is steadily increasing …

[HTML][HTML] Design and application in delivery system of intranasal antidepressants

J Xu, J Tao, J Wang - Frontiers in Bioengineering and Biotechnology, 2020 - frontiersin.org
One of the major reasons why depressed patients fail their treatment course is the existence
of the blood-brain barrier (BBB), which prevents drugs from being delivered to the central …

Microemulsions: a novel approach to enhanced drug delivery

S Talegaonkar, A Azeem, FJ Ahmad… - Recent patents on …, 2008 - ingentaconnect.com
Microemulsions are isotropic, thermodynamically stable transparent (or translucent) systems
of oil, water and surfactant, frequently in combination with a cosurfactant with a droplet size …

Time-dependent translocation and potential impairment on central nervous system by intranasally instilled TiO2 nanoparticles

J Wang, Y Liu, F Jiao, F Lao, W Li, Y Gu, Y Li, C Ge… - Toxicology, 2008 - Elsevier
Nanoparticles can be administered via nasal, oral, intraocular, intratracheal (pulmonary
toxicity), tail vein and other routes. Here, we focus on the time-dependent translocation and …

Formulation and Optimization of Polymeric Nanoparticles for Intranasal Delivery of Lorazepam Using Box‐Behnken Design: In Vitro and In Vivo Evaluation

D Sharma, D Maheshwari, G Philip… - BioMed research …, 2014 - Wiley Online Library
The aim of the present study was to optimize lorazepam loaded PLGA nanoparticles (Lzp‐
PLGA‐NPs) by investigating the effect of process variables on the response using Box …

A review of intranasal formulations for the treatment of seizure emergencies

M Kapoor, JC Cloyd, RA Siegel - Journal of Controlled Release, 2016 - Elsevier
Epileptic seizure emergencies are life-threatening conditions, which in their most severe
form, status epilepticus, have a high mortality rate if not quickly terminated. Treatment …

Human brain/cloud interface

NRB Martins, A Angelica, K Chakravarthy… - Advances in Clinical …, 2021 - taylorfrancis.com
The application of nanorobots to the human brain is denoted as “neuralnanorobotics.” This
technology may allow for the monitoring, recording, and even manipulation of many types of …

[PDF][PDF] Review on microemulsion as futuristic drug delivery

F Muzaffar, UK Singh, L Chauhan - Int J Pharm Pharm Sci, 2013 - edisciplinas.usp.br
Since the discovery of microemulsions by Jack H. Shulman, there have been huge
progresses made in applying microemulsion syst ems in a plethora of research and …