Encore: Behavioural animal models of stress, depression and mood disorders
A Petković, D Chaudhury - Frontiers in behavioral neuroscience, 2022 - frontiersin.org
Animal studies over the past two decades have led to extensive advances in our
understanding of pathogenesis of depressive and mood disorders. Among these, rodent …
understanding of pathogenesis of depressive and mood disorders. Among these, rodent …
Assessing negative affect in mice during abstinence from alcohol drinking: Limitations and future challenges
Alcohol use disorder (AUD) is frequently comorbid with mood disorders, and these co-
occurring neuropsychiatric disorders contribute to the development and maintenance of …
occurring neuropsychiatric disorders contribute to the development and maintenance of …
Microglia control escalation of drinking in alcohol-dependent mice: genomic and synaptic drivers
Background Microglia, the primary immune cells of the brain, are implicated in alcohol use
disorder. However, it is not known if microglial activation contributes to the transition from …
disorder. However, it is not known if microglial activation contributes to the transition from …
Endocannabinoid control of the insular-bed nucleus of the stria terminalis circuit regulates negative affective behavior associated with alcohol abstinence
SW Centanni, BD Morris, JR Luchsinger… - …, 2019 - nature.com
Negative affect is a core symptom domain associated with an array of neurological and
psychiatric disorders and is only partially targeted by current therapies, highlighting the need …
psychiatric disorders and is only partially targeted by current therapies, highlighting the need …
Nrf2 activation rescues stress-induced depression-like behaviour and inflammatory responses in male but not female rats
RT McCallum, RK Thériault, JD Manduca… - Biology of sex …, 2024 - Springer
Background Major depressive disorder (MDD) is a recurring affective disorder that is two
times more prevalent in females than males. Evidence supports immune system dysfunction …
times more prevalent in females than males. Evidence supports immune system dysfunction …
Cocaine and amphetamine regulated transcript (CART) mediates sex differences in binge drinking through central taste circuits
XJ Maddern, B Letherby, SS Ch'ng, A Pearl… - …, 2024 - nature.com
The neuropeptide cocaine-and amphetamine-regulated transcript (CART) has been
implicated in alcohol consumption and reward behaviours, yet mechanisms mediating these …
implicated in alcohol consumption and reward behaviours, yet mechanisms mediating these …
Sex differences in binge alcohol drinking and the behavioral consequences of protracted abstinence in C57BL/6J mice
JK Rivera-Irizarry, LJ Zallar, OB Levine… - Biology of sex …, 2023 - Springer
Background Binge alcohol drinking is a risk factor linked to numerous disease states
including alcohol use disorder (AUD). While men binge drink more alcohol than women, this …
including alcohol use disorder (AUD). While men binge drink more alcohol than women, this …
Binge-like alcohol exposure in adolescence: behavioural, neuroendocrine and molecular evidence of abnormal neuroplasticity… and return
A Brancato, V Castelli, G Lavanco, G Tringali, V Micale… - Biomedicines, 2021 - mdpi.com
Binge alcohol consumption among adolescents affects the developing neural networks
underpinning reward and stress processing in the nucleus accumbens (NAc). This study …
underpinning reward and stress processing in the nucleus accumbens (NAc). This study …
Ketamine and MAG lipase inhibitor-dependent reversal of evolving depressive-like behavior during forced abstinence from alcohol drinking
KM Holleran, HH Wilson, TL Fetterly, RJ Bluett… - …, 2016 - nature.com
Although alcoholism and depression are highly comorbid, treatment options that take this
into account are lacking, and mouse models of alcohol (ethanol (EtOH)) intake-induced …
into account are lacking, and mouse models of alcohol (ethanol (EtOH)) intake-induced …
The histone deacetylase inhibitor suberoylanilide hydroxamic acid (SAHA) alleviates depression-like behavior and normalizes epigenetic changes in the …
Withdrawal from chronic alcohol drinking can cause depression, leading to an inability to
function in daily life and an increased risk for relapse to harmful drinking. Understanding the …
function in daily life and an increased risk for relapse to harmful drinking. Understanding the …