Liver regeneration is a complex process involving the crosstalk of multiple cell types,
including hepatocytes, hepatic stellate cells, endothelial cells and inflammatory cells. The …

Although liver transplantation is a true success story, many patients still die awaiting an
organ. The increasing need for liver grafts therefore remains an unsolved challenge to the …

Current organ preservation methods provide a narrow window (usually< 12 hours) to
assess, transport and implant donor grafts for human transplantation. Here we report the …

Background & Aims Liver graft utilization rates are a hot topic due to the worldwide organ
shortage and the increasing number of transplant candidates on waiting lists. Liver perfusion …

A short period (1–2 h) of hypothermic oxygenated machine perfusion (HOPE) after static
cold storage is safe and reduces ischemia‐reperfusion injury‐related complications after …

A lack of accepted standards and standardized phantoms suitable for the technical
validation of biophotonic instrumentation hinders the reliability and reproducibility of its …

The limited preservation duration of organs has contributed to the shortage of organs for
transplantation. Recently, a tripling of the storage duration was achieved with supercooling …

The shortage of donor livers considered suitable for transplantation has driven the
development of novel methods for organ preservation and reconditioning. Machine …

Liver transplantation has become an immense success; nevertheless, far more recipients
are registered on waiting lists than there are available donor livers for transplantation. High …

Human cholangiocyte organoids are promising for regenerative medicine applications, such
as repair of damaged bile ducts. However, organoids are typically cultured in mouse tumor …