Single-molecule localization microscopy
Single-molecule localization microscopy (SMLM) describes a family of powerful imaging
techniques that dramatically improve spatial resolution over standard, diffraction-limited …
techniques that dramatically improve spatial resolution over standard, diffraction-limited …
Super-resolution microscopy for structural cell biology
Super-resolution microscopy techniques, and specifically single-molecule localization
microscopy (SMLM), are approaching nanometer resolution inside cells and thus have great …
microscopy (SMLM), are approaching nanometer resolution inside cells and thus have great …
Lens-free on-chip 3D microscopy based on wavelength-scanning Fourier ptychographic diffraction tomography
Lens-free on-chip microscopy is a powerful and promising high-throughput computational
microscopy technique due to its unique advantage of creating high-resolution images across …
microscopy technique due to its unique advantage of creating high-resolution images across …
Deep learning massively accelerates super-resolution localization microscopy
The speed of super-resolution microscopy methods based on single-molecule localization,
for example, PALM and STORM, is limited by the need to record many thousands of frames …
for example, PALM and STORM, is limited by the need to record many thousands of frames …
Field-dependent deep learning enables high-throughput whole-cell 3D super-resolution imaging
Single-molecule localization microscopy in a typical wide-field setup has been widely used
for investigating subcellular structures with super resolution; however, field-dependent …
for investigating subcellular structures with super resolution; however, field-dependent …
Technological advances in super-resolution microscopy to study cellular processes
C Bond, AN Santiago-Ruiz, Q Tang, M Lakadamyali - Molecular Cell, 2022 - cell.com
Since its initial demonstration in 2000, far-field super-resolution light microscopy has
undergone tremendous technological developments. In parallel, these developments have …
undergone tremendous technological developments. In parallel, these developments have …
CaMKII activation persistently segregates postsynaptic proteins via liquid phase separation
T Hosokawa, PW Liu, Q Cai, JS Ferreira, F Levet… - Nature …, 2021 - nature.com
Transient information input to the brain leads to persistent changes in synaptic circuits,
contributing to the formation of memory engrams. Pre-and postsynaptic structures undergo …
contributing to the formation of memory engrams. Pre-and postsynaptic structures undergo …
Enhanced detection of fluorescence fluctuations for high-throughput super-resolution imaging
High-throughput super-resolution (SR) imaging is attractive for rapid and high-precision
profiling in a wide range of biomedical applications. However, current SR methods require …
profiling in a wide range of biomedical applications. However, current SR methods require …
A robust unsupervised machine-learning method to quantify the morphological heterogeneity of cells and nuclei
Cell morphology encodes essential information on many underlying biological processes. It
is commonly used by clinicians and researchers in the study, diagnosis, prognosis, and …
is commonly used by clinicians and researchers in the study, diagnosis, prognosis, and …
MemBright: a family of fluorescent membrane probes for advanced cellular imaging and neuroscience
The proper staining of the plasma membrane (PM) is critical in bioimaging as it delimits the
cell. Herein, we developed MemBright, a family of six cyanine-based fluorescent turn-on PM …
cell. Herein, we developed MemBright, a family of six cyanine-based fluorescent turn-on PM …