The therapeutic benefits of the current medications for patients with psychiatric disorders
contrast with a great variety of adverse effects. The endocannabinoid system (ECS) …

Stress is a frequent precipitant of relapse to drug use. Pharmacotherapies targeting a
diverse array of neural systems have been assayed for efficacy in attenuating stress-induced …

Prefrontal cortex (PFC) maturation during adolescence is characterized by structural and
functional changes, which involve the remodeling of GABA and glutamatergic synapses, as …

The ubiquitous distribution of the classic endocannabinoid system (cannabinoid receptors
CB1 and CB2) has been demonstrated within the monkey nervous system, including the …

Part of the ventral striatal division, the nucleus accumbens (NAc) drives the circuit activity of
an entire macrosystem about reward like a “flagship,” signaling and leading diverse …

Introduction The endocannabinoid (eCB) system is named after the discovery that
endogenous cannabinoids bind to the same receptors as the phytochemical compounds …

The claustrum (Cl) is a subcortical nucleus present in all mammalian species examined so
far, whose function is still a puzzling problem. There is a wealth of data on its general …

The fatty acid amide hydrolase (FAAH, EC 3.5. 1.99) is an integral intracellular membrane-
bound enzyme that was properly characterized in the mid-1980s, 1 although an N …

Vervets (Chlorocebus spp.), also known as African green monkeys or savanna monkeys, are
Old World monkeys that are frequently studied in biomedical research. Research areas have …

The expression of the endocannabinoid (eCB) system, including cannabinoid receptor type
1 (CB1R) and the cannabinoid synthesizing (NAPE-PLD) and degrading (FAAH) enzymes …