Regulation of placental extravillous trophoblasts by the maternal uterine environment

J Pollheimer, S Vondra, J Baltayeva… - Frontiers in …, 2018 - frontiersin.org
During placentation invasive extravillous trophoblasts (EVTs) migrate into the maternal
uterus and modify its vessels. In particular, remodeling of the spiral arteries by EVTs is …

Mechanisms of implantation: strategies for successful pregnancy

J Cha, X Sun, SK Dey - Nature medicine, 2012 - nature.com
Physiological and molecular processes initiated during implantation for pregnancy success
are complex but highly organized. This review primarily highlights adverse ripple effects …

Single-cell transcriptomic atlas of the human endometrium during the menstrual cycle

W Wang, F Vilella, P Alama, I Moreno, M Mignardi… - Nature Medicine, 2020 - nature.com
In a human menstrual cycle the endometrium undergoes remodeling, shedding and
regeneration, all of which are driven by substantial gene expression changes in the …

Development of organoids from mouse and human endometrium showing endometrial epithelium physiology and long-term expandability

M Boretto, B Cox, M Noben, N Hendriks… - …, 2017 - journals.biologists.com
The endometrium, which is of crucial importance for reproduction, undergoes dynamic cyclic
tissue remodeling. Knowledge of its molecular and cellular regulation is poor, primarily …

The role of mesenchymal–epithelial transition in endometrial function

A Owusu-Akyaw, K Krishnamoorthy… - Human reproduction …, 2019 - academic.oup.com
BACKGROUND The human uterine endometrium undergoes significant remodeling and
regeneration on a rapid and repeated basis, after parturition, menstruation, and in some …

Placental trophoblast cell differentiation: physiological regulation and pathological relevance to preeclampsia

L Ji, J Brkić, M Liu, G Fu, C Peng, YL Wang - Molecular aspects of medicine, 2013 - Elsevier
The placenta is a transient organ that forms during pregnancy to support the growth and
development of the fetus. During human placental development, trophoblast cells …

Endometrial decidualization: of mice and men

CY Ramathal, IC Bagchi, RN Taylor… - Seminars in …, 2010 - thieme-connect.com
In murine and human pregnancies, embryos implant by attaching to the luminal epithelium
and invading into the stroma of the endometrium. Under the influence of the steroid …

Human placental trophoblast invasion and differentiation: a particular focus on Wnt signaling

M Knöfler, J Pollheimer - Frontiers in genetics, 2013 - frontiersin.org
Wingless ligands, a family of secreted proteins, are critically involved in organ development
and tissue homeostasis by ensuring balanced rates of stem cell proliferation, cell death and …

WNT and NOTCH signaling in human trophoblast development and differentiation

B Dietrich, S Haider, G Meinhardt, J Pollheimer… - Cellular and Molecular …, 2022 - Springer
Correct development of the human placenta and its differentiated epithelial cells, syncytial
trophoblasts (STBs) and extravillous trophoblasts (EVTs), is crucial for a successful …

Gene expression analysis of endometrium reveals progesterone resistance and candidate susceptibility genes in women with endometriosis

RO Burney, S Talbi, AE Hamilton, KC Vo… - …, 2007 - academic.oup.com
The identification of molecular differences in the endometrium of women with endometriosis
is an important step toward understanding the pathogenesis of this condition and toward …