[HTML][HTML] Intratumoral microbiota: roles in cancer initiation, development and therapeutic efficacy

L Yang, A Li, Y Wang, Y Zhang - Signal transduction and targeted …, 2023 - nature.com
Microorganisms, including bacteria, viruses, fungi, and other eukaryotes, play critical roles in
human health. An altered microbiome can be associated with complex diseases …

[HTML][HTML] Mechanisms and regulation of defensins in host defense

J Fu, X Zong, M Jin, J Min, F Wang… - Signal Transduction and …, 2023 - nature.com
As a family of cationic host defense peptides, defensins are mainly synthesized by Paneth
cells, neutrophils, and epithelial cells, contributing to host defense. Their biological functions …

Good gone bad: one toxin away from disease for Bacteroides fragilis

E Valguarnera, JB Wardenburg - Journal of molecular biology, 2020 - Elsevier
The human gut is colonized by hundreds of trillions of microorganisms whose acquisition
begins during early infancy. Species from the Bacteroides genus are ubiquitous …

[HTML][HTML] Human β-defensin 2 and its postulated role in modulation of the immune response

M Cieślik, N Bagińska, A Górski, E Jończyk-Matysiak - Cells, 2021 - mdpi.com
Studies described so far suggest that human β-defensin 2 is an important protein of innate
immune response which provides protection for the human organism against invading …

Mechanisms of parenteral nutrition–associated liver and gut injury

H Madnawat, AL Welu, EJ Gilbert… - Nutrition in Clinical …, 2020 - Wiley Online Library
Parenteral nutrition (PN) has revolutionized the care of patients with intestinal failure by
providing nutrition intravenously. Worldwide, PN remains a standard tool of nutrition delivery …

[HTML][HTML] A systemic review of the role of enterotoxic Bacteroides fragilis in colorectal cancer

N Scott, E Whittle, P Jeraldo, N Chia - Neoplasia, 2022 - Elsevier
Enterotoxigenic Bacteroides fragilis (ETBF) has received significant attention for a possible
association with, or causal role in, colorectal cancer (CRC). The goal of this review was to …

[HTML][HTML] Vascular smooth muscle-MAPK14 is required for neointimal hyperplasia by suppressing VSMC differentiation and inducing proliferation and inflammation

W Wu, W Zhang, M Choi, J Zhao, P Gao, M Xue… - Redox biology, 2019 - Elsevier
Injury-induced stenosis is a serious vascular complication. We previously reported that p38α
(MAPK14), a redox-regulated p38MAPK family member was a negative regulator of the …

Lower systemic inflammation is associated with gut firmicutes dominance and reduced liver injury in a novel ambulatory model of parenteral nutrition

A Samaddar, J van Nispen, A Armstrong… - Annals of …, 2022 - Taylor & Francis
Abstract Background Total Parenteral Nutrition (TPN) provides lifesaving nutritional support
to patients unable to maintain regular enteral nutrition (EN). Unfortunately, cholestasis is a …

Effect of the oral intake of yogurt containing Bifidobacterium longum BB536 on the cell numbers of enterotoxigenic Bacteroides fragilis in microbiota

T Odamaki, H Sugahara, S Yonezawa, T Yaeshima… - Anaerobe, 2012 - Elsevier
Enterotoxigenic Bacteroides fragilis (ETBF) strains have been suggested to be associated
with acute and persistent diarrheal disease, inflammatory bowel disease and colorectal …

[HTML][HTML] Ferulic acid metabolites attenuate LPS-induced inflammatory response in enterocyte-like cells

G Serreli, MR Naitza, S Zodio, VP Leoni, M Spada… - Nutrients, 2021 - mdpi.com
Ferulic acid (FA) is a polyphenol pertaining to the class of hydroxycinnamic acids present in
numerous foods of a plant origin. Its dietary consumption leads to the formation of several …