Patients with major depressive disorder (MDD) often exhibit an inadequate treatment
response or failure to achieve remission following treatment with antidepressant drugs …

Depression is associated with general medical conditions (GMCs), but it is not known if
treatment-resistant depression (TRD) affects GMC risk and vice versa. We estimated …

Abstract Treatment-resistant depression (TRD) is a severe form of major depressive disorder
(MDD) with substantial public health impact and poor treatment outcome. Treatment …

Objective Investigate incidence, risk factors and courses of treatment for treatment-resistant
depression (TRD) in primary and special healthcare. Methods All patients identified from …

Objective Treatment-resistant depression (TRD) has been associated with higher mortality
and risk of suicide, but this has mainly been showed in few studies which did not include self …

Objective: To describe treatment patterns in patients with treatment-resistant depression
(TRD) and major depressive disorder (MDD) stratified by depression severity and year of …

Background Despite numerous national depression care guidelines (DCGs), suboptimal
antidepressant treatment may occur. We examined DCG concordance and depression …

Background Previous studies have not investigated response rates after electroconvulsive
therapy (ECT) in patients with non-psychotic treatment-resistant depression (TRD). Aims To …

Background: Patients with treatment-resistant depression (TRD) have an increased mortality
risk compared with other patients with depression, but it is not known how this translates into …

Background Due to its relatively high prevalence and recurrent nature, depression causes a
major burden on healthcare systems, societies and individuals. Our objective was to …