The Parkinson's Progression Markers Initiative (PPMI) has collected more than a decade's
worth of longitudinal and multi-modal data from patients, healthy controls, and at-risk …

Depression, with an estimated prevalence of about 40% is a most common neuropsychiatric
disorder in Parkinson disease (PD), with a negative impact on quality of life, cognitive …

Optical coherence tomography is a noninvasive imaging technology using the optical
reflectivity of tissues that is capable of detecting quantitative and qualitative biomarkers of …

Parkinson disease (PD) is well recognized as a complex neurodegenerative disorder with a
myriad of motor and nonmotor symptoms. 1, 2 Nonmotor symptoms can predate the classic …

Depression, a leading cause of disability worldwide, is also the most prevalent psychiatric
problem among Parkinson disease patients. Both depression and Parkinson disease are …

Background and Objectives: Parkinson's disease (PD) is a clinically heterogeneous disorder
with poorly understood pathological contributing factors. Depression presents one of the …

Background: A genome-wide association study (GWAS) variant associated with Parkinson's
disease (PD) risk in Asians, rs9638616, was recently reported, and maps to …

As an emerging research field of brain science, multimodal data fusion analysis has
attracted broader attention in the study of complex brain diseases such as Parkinson's …

Cover Page The handle http://hdl.handle.net/1887/138480 holds various files of this Leiden
University dissertation. Author: Keo, Page 1 Cover Page The handle http://hdl.handle.net/1887/138480 …