Background Challenges of “standardisation” and “individualisation” have always been
characteristic for medical services. In terms of individualisation, the best possible individual …

Background. Biobanks are vital research infrastructures aiming to collect, process, store, and
distribute biological specimens along with associated data in an organized and governed …

Research with human subjects 1 exemplifies the perennial conflict between the good of the
individual and the good of society. Policies and procedures that protect the rights and …

Background Increasing evidence linking epigenetic mechanisms and different diseases,
including cancer, has prompted in the last 15 years the investigation of histone post …

Background Biobanks provide an important foundation for genomic and personalised
medicine. In order to enhance their scientific power and scope, they are increasingly …

Aberrations in histone post-translational modifications (PTMs), as well as in the histone
modifying enzymes (HMEs) that catalyze their deposition and removal, have been reported …

Biobanks are key research infrastructures aimed at the collection, storage, processing, and
sharing of high-quality human biological samples and associated data for research …

Abstract 'Right To Try'(RTT) laws originated in the USA to allow terminally ill patients to
request access to early stage experimental medical products directly from the producer …

Histone post-translational modifications (PTMs) have crucial roles in a multitude of cellular
processes, and their aberrant levels have been linked with numerous diseases, including …

Epigenetic aberrations have been recognized as important contributors to cancer onset and
development, and increasing evidence suggests that linker histone H1 variants may serve …