Constipation is broadly defined as an unsatisfactory defecation characterized by infrequent
stools, difficult stool passage or both. The common approach to the pathophysiology of …

Disorders of the anorectum and pelvic floor affect approximately 25% of the population.
Their evaluation and treatment have been hindered by a lack of understanding of underlying …

Pelvic floor failure is a common disorder that can seriously jeopardize a woman's quality of
life by causing urinary and fecal incontinence, difficult defecation, and pelvic pain. Multiple …

Human motor cortex can activate pelvic floor muscles (PFM), but the motor cortical
representation of the PFM is not well characterized. PFM representation is thought to be …

BACKGROUND: Neurologic dysfunction causes fecal incontinence, but current techniques
for its assessment are limited and controversial. OBJECTIVE: The purpose of this work was …

OBJECTIVES: Spinal cord injury (SCI) causes anorectal problems, whose pathophysiology
remains poorly characterized. A comprehensive method of evaluating spino-anorectal …

Background Chronic idiopathic constipation (CIC) is a condition that widely affects the global
population, represents relevant healthcare resource utilization and costs, and impacts the …

Constipation and fecal incontinence (FI) are common complaints predominantly affecting the
elderly and women. They are associated with significant morbidity and high healthcare …

Recent evidence shows that consensual anal penetrative intercourse has become more
prevalent, not only limited to gay, bisexual, and other men who have sex with men but also …

The normal function of the anal sphincter complex is crucial for quality of life, as it is the
mechanism by which fecal continence is maintained. Additionally, the anal sphincter …