Peptide arrays: development and application
Peptide arrays are an exciting and rapidly growing technology with a broad range of
applications in the basic and applied life sciences. Peptide arrays have been under …
applications in the basic and applied life sciences. Peptide arrays have been under …
Overcoming symmetry mismatch in vaccine nanoassembly through spontaneous amidation
Matching of symmetry at interfaces is a fundamental obstacle in molecular assembly. Virus‐
like particles (VLPs) are important vaccine platforms against pathogenic threats, including …
like particles (VLPs) are important vaccine platforms against pathogenic threats, including …
Differing efficacies of lead group A streptococcal vaccine candidates and full-length M protein in cutaneous and invasive disease models
ABSTRACT Group A Streptococcus (GAS) is an important human pathogen responsible for
both superficial infections and invasive diseases. Autoimmune sequelae may occur upon …
both superficial infections and invasive diseases. Autoimmune sequelae may occur upon …
Group A Streptococcus vaccine targeting the erythrogenic toxins SpeA and SpeB is safe and immunogenic in rabbits and does not induce antibodies associated with …
MJ Troese, E Burlet, MW Cunningham, K Alvarez… - Vaccines, 2023 - mdpi.com
Group A streptococcus (GAS) is a global pathogen associated with significant morbidity and
mortality for which there is currently no licensed vaccine. Vaccine development has been …
mortality for which there is currently no licensed vaccine. Vaccine development has been …
WHO/IVI global stakeholder consultation on group A Streptococcus vaccine development: report from a meeting held on 12–13 December 2016
J Osowicki, J Vekemans, DC Kaslow, MH Friede… - Vaccine, 2018 - Elsevier
While progress towards a Group A Streptococcus (GAS) vaccine has been stalled by a
combination of scientific, regulatory, and commercial barriers, the problem persists. The high …
combination of scientific, regulatory, and commercial barriers, the problem persists. The high …
Conserved molecular chaperone PrsA stimulates protective immunity against group A Streptococcus
CY Lai, JX Xie, MC Lai, ZY Wu, JS Lin, YT Huang… - npj Vaccines, 2024 - nature.com
Abstract Group A Streptococcus (GAS) is a significant human pathogen that poses a global
health concern. However, the development of a GAS vaccine has been challenging due to …
health concern. However, the development of a GAS vaccine has been challenging due to …
A general approach for predicting protein epitopes targeted by antibody repertoires using whole proteomes
Antibodies are essential to functional immunity, yet the epitopes targeted by antibody
repertoires remain largely uncharacterized. To aid in characterization, we developed a …
repertoires remain largely uncharacterized. To aid in characterization, we developed a …
[HTML][HTML] New modular platform based on multi-adjuvanted amphiphilic chitosan nanoparticles for efficient lipopeptide vaccine delivery against group A streptococcus
An effective vaccine against group A streptococcus (GAS) is highly desirable for definitive
control of GAS infections. In the present study, two variants of amphiphilic chitosan …
control of GAS infections. In the present study, two variants of amphiphilic chitosan …
Immunization with the lipoprotein FtsB stimulates protective immunity against Streptococcus pyogenes infection in mice
LY He, YB Yu, Y Liu, YJ Le, S Li, XY Yang - Frontiers in Microbiology, 2022 - frontiersin.org
Streptococcus pyogenes is one of the main pathogenic bacteria that causes disease in
humans. It is reported that over 18 million cases of S. pyogenes disease occurred in the …
humans. It is reported that over 18 million cases of S. pyogenes disease occurred in the …
[PDF][PDF] Vaccinazione esavalente: nuove evidenze scientifiche e falsi miti da sfatare
C Azzari, S Ricci, F Lippi, C Canessa - RIAP, 2017 - old.riaponline.it
La vaccinazione esavalente ha un'importanza fondamentale. Le malattie che vengono
prevenute mediante il vaccino esavalente sono tutte estremamente gravi e potenzialmente …
prevenute mediante il vaccino esavalente sono tutte estremamente gravi e potenzialmente …