Role of circRNAs in neurodevelopment and neurodegenerative diseases
J Li, C Sun, H Cui, J Sun, P Zhou - Journal of Molecular Neuroscience, 2021 - Springer
With the rapid development of sequencing technology, scientists have been able to study
and acquire a better understanding of non-coding RNAs (ncRNAs). Circular RNAs …
and acquire a better understanding of non-coding RNAs (ncRNAs). Circular RNAs …
[HTML][HTML] Epigenetic modulation of opioid receptors by drugs of abuse
KZ Reid, BM Lemezis, TC Hou, R Chen - International Journal of …, 2022 - mdpi.com
Chronic exposure to drugs of abuse produces profound changes in gene expression and
neural activity associated with drug-seeking and taking behavior. Dysregulation of opioid …
neural activity associated with drug-seeking and taking behavior. Dysregulation of opioid …
[HTML][HTML] Aerobic exercise improves VCI through circRIMS2/miR-186/BDNF-mediated neuronal apoptosis
Y Niu, C Wan, J Zhang, S Zhang, Z Zhao, L Zhu… - Molecular …, 2021 - Springer
Background Vascular cognitive impairment (VCI) is a common cognitive disorder caused by
cerebrovascular disease, ranging from mild cognitive impairment to dementia. Studies have …
cerebrovascular disease, ranging from mild cognitive impairment to dementia. Studies have …
[HTML][HTML] Heroin regulates orbitofrontal circular RNAs
The number of drug overdose deaths involving opioids continues to rise in the United States.
Many patients with opioid use disorder (OUD) that seek treatment still experience relapse …
Many patients with opioid use disorder (OUD) that seek treatment still experience relapse …
CircTmeff-1 in the nucleus accumbens regulates the reconsolidation of cocaine-associated memory
Q Shen, B Xie, E Galaj, H Yu, X Li, Y Lu, M Zhang… - Brain Research …, 2022 - Elsevier
Reconsolidation of drug memories is the process of restoring unstable memories after
unconditioned (UCS; eg, drugs) or conditioned stimulus (CS; eg, drug-paired contexts), and …
unconditioned (UCS; eg, drugs) or conditioned stimulus (CS; eg, drug-paired contexts), and …
[HTML][HTML] CircSYNDIG1 ameliorates stress-induced abnormal behaviors by suppressing miR-344-5p in mice
X Wang, H Song, Y Du, Y Zhao, Y Fu, Q Meng… - Brain research …, 2023 - Elsevier
Circular RNA (circRNA) plays an important role in diverse stress-related neuropsychiatric
disorders like depression, anxiety and cognitive disorders. Here, using a circRNA …
disorders like depression, anxiety and cognitive disorders. Here, using a circRNA …
Orbitofrontal intronic circular RNA from Nrxn3 mediates reward learning and motivation for reward
The orbitofrontal cortex (OFC) is a vital component of brain reward circuitry that is important
for reward seeking behavior. However, OFC-mediated molecular mechanisms underlying …
for reward seeking behavior. However, OFC-mediated molecular mechanisms underlying …
Comprehensive analysis of differential m6A RNA methylomes in the hippocampus of cocaine-conditioned mice
A Xue, Y Huang, M Li, Q Wei, Q Bu - Molecular Neurobiology, 2021 - Springer
Abstract N6-methyladenosine (m6A) is the most prevalent internal modification found in
mRNAs and lncRNA and plays a vital role in posttranscriptional regulation in mammals. m6A …
mRNAs and lncRNA and plays a vital role in posttranscriptional regulation in mammals. m6A …
[HTML][HTML] Prenatal alcohol exposure results in sex-specific alterations in circular RNA expression in the developing mouse brain
Fetal alcohol spectrum disorders (FASD) are heterogeneous disorders associated with
alcohol exposure to the developing fetus that are characterized by a range of adverse …
alcohol exposure to the developing fetus that are characterized by a range of adverse …
[HTML][HTML] Identification of Functional CircRNA–miRNA–mRNA Regulatory Network in Dorsolateral Prefrontal Cortex Neurons of Patients With Cocaine Use Disorder
Y Chen, X Li, S Meng, S Huang, S Chang… - Frontiers in Molecular …, 2022 - frontiersin.org
Increasing evidence has indicated that circular RNAs (circRNAs) act as competing
endogenous RNAs (ceRNAs) regulatory network to regulate the expression of target genes …
endogenous RNAs (ceRNAs) regulatory network to regulate the expression of target genes …