The bone marrow side of axial spondyloarthritis
Spondyloarthritis (SpA) is characterized by the infiltration of innate and adaptive immune
cells into entheses and bone marrow. Molecular, cellular and imaging evidence …
cells into entheses and bone marrow. Molecular, cellular and imaging evidence …
Enthesis repair–State of play
E Pugliese, A Rossoni, DI Zeugolis - Biomaterials Advances, 2024 - Elsevier
The fibrocartilaginous enthesis is a highly specialised tissue interface that ensures a smooth
mechanical transfer between tendon or ligament and bone through a fibrocartilage area …
mechanical transfer between tendon or ligament and bone through a fibrocartilage area …
Effects of mineralization on the hierarchical organization of collagen—a synchrotron X-ray scattering and polarized second harmonic generation study
The process of mineralization fundamentally alters collagenous tissue biomechanics. While
the structure and organization of mineral particles have been widely studied, the impact of …
the structure and organization of mineral particles have been widely studied, the impact of …
Optogenetic-induced muscle loading leads to mechanical adaptation of the Achilles tendon enthesis in mice
Skeletal shape depends on the transmission of contractile muscle forces from tendon to
bone across the enthesis. Loss of muscle loading impairs enthesis development, yet little is …
bone across the enthesis. Loss of muscle loading impairs enthesis development, yet little is …
[HTML][HTML] Hypertrophic chondrocytes at the junction of musculoskeletal structures
N Chen, RWH Wu, Y Lam, WCW Chan, D Chan - Bone Reports, 2023 - Elsevier
Hypertrophic chondrocytes are found at unique locations at the junction of skeletal tissues,
cartilage growth plate, articular cartilage, enthesis and intervertebral discs. Their role in the …
cartilage growth plate, articular cartilage, enthesis and intervertebral discs. Their role in the …
Decoding the mechanical characteristics of the human anterior cruciate ligament entheses through graduated mineralization interfaces
The anterior cruciate ligament is anchored to the femur and tibia via specialized interfaces
known as entheses. These play a critical role in ligament homeostasis and joint stability by …
known as entheses. These play a critical role in ligament homeostasis and joint stability by …
Upregulation of Runt related transcription factor 1 (RUNX1) contributes to tendon–bone healing after anterior cruciate ligament reconstruction using bone …
K Kang, Q Geng, L Cui, L Wu, L Zhang, T Li… - Journal of orthopaedic …, 2022 - Springer
Background Anterior cruciate ligament (ACL) injury could lead to functional impairment
along with disabilities. ACL reconstruction often fails owing to the regeneration failure of …
along with disabilities. ACL reconstruction often fails owing to the regeneration failure of …
Therapeutic Potential of Exosomes in Tendon and Tendon–Bone Healing: A Systematic Review of Preclinical Studies
M Zou, J Wang, Z Shao - Journal of Functional Biomaterials, 2023 - mdpi.com
Exosomes have been proven to play a positive role in tendon and tendon–bone healing.
Here, we systematically review the literature to evaluate the efficacy of exosomes in tendon …
Here, we systematically review the literature to evaluate the efficacy of exosomes in tendon …
[HTML][HTML] Impaired 1, 25-dihydroxyvitamin D3 action underlies enthesopathy development in the Hyp mouse model of X-linked hypophosphatemia
X-linked hypophosphatemia (XLH) is characterized by high serum fibroblast growth factor 23
(FGF23) levels, resulting in impaired 1, 25-dihydroxyvitamin D 3 (1, 25D) production. Adults …
(FGF23) levels, resulting in impaired 1, 25-dihydroxyvitamin D 3 (1, 25D) production. Adults …
[HTML][HTML] Recent developments in Achilles tendon risk-analyzing rupture factors for enhanced injury prevention and clinical guidance: Current implications of …
MV Sankova, NM Beeraka, MV Oganesyan… - Journal of Orthopaedic …, 2024 - Elsevier
Background In recent years, many countries have actively implemented programs and
strategies to promote physical education and sports. Despite these efforts, the increase in …
strategies to promote physical education and sports. Despite these efforts, the increase in …