Neonates have little immunological memory and a developing immune system, which
increases their vulnerability to infectious agents. Recent advances in the understanding of …

The mucosal surfaces of the gut and airways have important barrier functions and regulate
the induction of immunological tolerance. The rapidly increasing incidence of chronic …

Neonatal CD4+ and CD8+ T cells have historically been characterized as immature or
defective. However, recent studies prompt a reinterpretation of the functions of neonatal T …

Exiting from the largely sterile environment of the womb, the neonatal immune system is not
fully mature, and thus neonatal immune cells must simultaneously mount responses against …

BACKGROUND & AIMS: Chronic infection with the bacterial pathogen Helicobacter pylori
causes gastric disorders, ranging from chronic gastritis to gastric adenocarcinoma. Only a …

Immediately after cardiac injury, the immune system plays major roles in repair and
regeneration as it becomes involved in a number of processes including damage …

Helicobacter pylori has coexisted with humans for approximately 60,000 years and greater
than 50% of the global population is infected with H. pylori. H. pylori was successfully …

In comparison to adults, newborns display a heightened susceptibility to pathogens and a
propensity to develop allergic diseases. Particular properties of the neonatal immune system …

Unlike adult cardiomyocytes, neonatal cardiomyocytes can readily proliferate that
contributes to a transient regenerative potential after myocardial injury in mice. We have …

Aims Newborn mice and humans display transient cardiac regenerative potential that rapidly
declines postnatally. Patients who survive a myocardial infarction (MI) often develop chronic …