To coordinate, adapt and respond to biological signals, cells convey specific messages to
other cells. An important aspect of cell–cell communication involves secretion of molecules …

Extracellular vesicles (EVs) are biocompatible, nano‐sized secreted vesicles containing
many types of biomolecules, including proteins, RNAs, DNAs, lipids, and metabolites. Their …

Cellular membranes can form two principally different involutions, which either exclude or
contain cytosol. The 'classical'budding reactions, such as those occurring during …

Autophagy is fundamental for cell and organismal health. Two types of autophagy are
conserved in eukaryotes: macroautophagy and microautophagy. During macroautophagy …

The intraluminal vesicles (ILVs) of endosomes mediate the delivery of activated signaling
receptors and other proteins to lysosomes for degradation, but they also modulate …

Eukaryotic cells maintain a highly organized endolysosomal system. This system regulates
the protein and lipid content of the plasma membrane, it participates in the intracellular …

The late endosomes/endo‐lysosomes of vertebrates contain an atypical phospholipid,
lysobisphosphatidic acid (LBPA)(also termed bis [monoacylglycero] phosphate [BMP]) …

Lysosomes are key cellular catabolic centers that also perform fundamental metabolic,
signaling and quality control functions. Lysosomes are not static and they respond …

The endosomal sorting complex required for transport-III (ESCRT-III) catalyzes membrane
fission from within membrane necks, a process that is essential for many cellular functions …

The endosomal sorting complexes required for transport (ESCRT) pathway mediates
cellular membrane remodeling and fission reactions. The pathway comprises five core …