The surface wrinkling of biological tissues is ubiquitous in nature. Accumulating evidence
suggests that the mechanical force plays a significant role in shaping the biological …

Cortical folding, or gyrification, coincides with several important developmental processes.
The folded shape of the human brain allows the cerebral cortex, the thin outer layer of …

Convolutions are a classical hallmark of most mammalian brains. Brain surface morphology
is often associated with intelligence and closely correlated with neurological dysfunction …

Folding of the cerebral cortex is a prominent characteristic of mammalian brains. Alterations
or deficits in cortical folding are strongly correlated with abnormal brain function, cognition …

The important mechanical parameters and their hierarchy in the growth and folding of the
human brain have not been thoroughly understood. In this study, we developed a multiscale …

Cortical thickness varies throughout the cortex in a systematic way. However, it is
challenging to investigate the patterns of cortical thickness due to the intricate geometry of …

Cortical folding is an important process during brain development, and aberrant folding is
linked to disorders such as autism and schizophrenia. Changes in cell numbers, size, and …

The human brain has a highly complex structure both on the microscopic and on the
macroscopic scales. Increasing evidence has suggested the role of mechanical forces for …

Cortical folding is one of the most complex processes that occur during the normal
development of the human brain. Despite variability in folding patterns of different …

The process of gyrification, by which the brain develops the intricate pattern of gyral hills and
sulcal valleys, is the result of interactions between biological and mechanical processes …