Pathways to zoonotic spillover

RK Plowright, CR Parrish, H McCallum… - Nature Reviews …, 2017 - nature.com
Zoonotic spillover, which is the transmission of a pathogen from a vertebrate animal to a
human, presents a global public health burden but is a poorly understood phenomenon …

Global morbidity and mortality of leptospirosis: a systematic review

F Costa, JE Hagan, J Calcagno, M Kane… - PLoS neglected …, 2015 - journals.plos.org
Background Leptospirosis, a spirochaetal zoonosis, occurs in diverse epidemiological
settings and affects vulnerable populations, such as rural subsistence farmers and urban …

Leptospirosis: a neglected tropical zoonotic infection of public health importance—an updated review

KB Karpagam, B Ganesh - European Journal of Clinical Microbiology & …, 2020 - Springer
Leptospirosis is a zoonotic and waterborne disease worldwide. It is a neglected, reemerging
disease of global public health importance with respect to morbidity and mortality both in …

Impact of preexisting dengue immunity on Zika virus emergence in a dengue endemic region

I Rodriguez-Barraquer, F Costa, EJM Nascimento… - Science, 2019 - science.org
The clinical outcomes associated with Zika virus (ZIKV) in the Americas have been well
documented, but other aspects of the pandemic, such as attack rates and risk factors, are …

Spatiotemporal determinants of urban leptospirosis transmission: four-year prospective cohort study of slum residents in Brazil

JE Hagan, P Moraga, F Costa, N Capian… - PLoS neglected …, 2016 - journals.plos.org
Background Rat-borne leptospirosis is an emerging zoonotic disease in urban slum
settlements for which there are no adequate control measures. The challenge in elucidating …

Epidemiology of human leptospirosis in urban and rural areas of Brazil, 2000–2015

DI Galan, AA Roess, SVC Pereira, MC Schneider - PLoS One, 2021 - journals.plos.org
Background Leptospirosis is one of the most widespread zoonosis in the world and Brazil
has the highest number of cases in Latin America. Transmission occurs mainly through …

Insects, rodents, and pets as reservoirs, vectors, and sentinels of antimicrobial resistance

W Gwenzi, N Chaukura, N Muisa-Zikali, C Teta… - Antibiotics, 2021 - mdpi.com
This paper reviews the occurrence of antimicrobial resistance (AMR) in insects, rodents, and
pets. Insects (eg, houseflies, cockroaches), rodents (rats, mice), and pets (dogs, cats) act as …

Leptospirosis and the environment: A review and future directions

EA Bradley, G Lockaby - Pathogens, 2023 - mdpi.com
Leptospirosis is a zoonotic disease of global importance with significant morbidity and
mortality. However, the disease is frequently overlooked and underdiagnosed, leading to …

Patterns in Leptospira Shedding in Norway Rats (Rattus norvegicus) from Brazilian Slum Communities at High Risk of Disease Transmission

F Costa, EA Wunder Jr, D De Oliveira… - PLoS neglected …, 2015 - journals.plos.org
Background We address some critical but unknown parameters of individuals and
populations of Norway rats (Rattus norvegicus) that influence leptospiral infection …

Investigating the Immunological and Biological Equilibrium of Reservoir Hosts and Pathogenic Leptospira: Balancing the Solution to an Acute Problem?

EJ Putz, JE Nally - Frontiers in microbiology, 2020 - frontiersin.org
Leptospirosis is a devastating zoonotic disease affecting people and animals across the
globe. Pathogenic leptospires are excreted in urine of reservoir hosts which directly or …